songorine

songorine Basic information

Product Name:	songorine
Synonyms:	(20R)-21-Ethyl-1α,15β-dihydroxy-4-methyl-16-methylene-7α,20-cycloveatchan-12-one;Napellonine;Zongorine;(3R,6S,6aR,6bR,9R,11R,11aR,12R,12aR,14R)-1-Ethyldodecahydro-6,11-dihydroxy-3-methyl-10-methylene-12,3,6a-ethanylylidene-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one;Napellonin;Xuan-Wu 2;Songorine,BullatineG;ShiMoburo base I
CAS:	509-24-0
MF:	C22H31NO3
MW:	357.49
EINECS:	200-158-5
Product Categories:	chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol File:	509-24-0.mol

songorine Chemical Properties

Melting point	201-203℃
alpha	D20 -135.4°
Boiling point	535.8±50.0 °C(Predicted)
density	1.29
solubility	DMF: 10 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 5 mg/ml; Ethanol: slightly soluble
form	A solid
pka	14.20±0.60(Predicted)

Safety Information

Toxicity

LD50 in mice (mg/kg): 1575 orally, 630 s.c., 485 i.p., 142.5 i.v.; in rats (mg/kg): 407.5 i.p. (Bisset)

MSDS Information

songorine Usage And Synthesis

Uses	Songorine is an extract from the Aconitum flavum root and may act as an inhibitor of JNK and p53 enhancing stimulation of fibroblast colony/cluster formation and proliferative activity of mesosomal precursors.

songorine Preparation Products And Raw materials

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