(1R,3S)-Benazepril Hydrochloride

(1R,3S)-Benazepril Hydrochloride Basic information
Product Name:(1R,3S)-Benazepril Hydrochloride
Synonyms:1H-1-Benzazepine-1-acetic acid, 3-[[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-;1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R*,S*)]-;2-((S)-3-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)aceticacidhydrochloride;(1R,3S)-Benazepril Hydrochloride;Benner Pury hydrochloride;Benazepril USP RC B;Benazepril Related CoMpound B;Benazepril USP Related Compound B
CAS:86541-77-7
MF:C24H28N2O5HCl
MW:460.96
EINECS:
Product Categories:API intermediates
Mol File:86541-77-7.mol
(1R,3S)-Benazepril Hydrochloride Structure
(1R,3S)-Benazepril Hydrochloride Chemical Properties
Melting point 181-183 °C(Solv: 2-butanone (78-93-3))
Safety Information
HS Code 2933790002
MSDS Information
(1R,3S)-Benazepril Hydrochloride Usage And Synthesis
Uses(1R,3S)-Benazepril Hydrochloride is an isomer of Benazepril (B119750), an angiotensin converting enzyme inhibitor and a antihypertensive agent.
General DescriptionBenazepril hydrochloride,(3S)-3-[[(1S)-1-carbethoxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid 3-ethylester hydrochloride (Lotensin), is metabolized rapidly to theactive diacid benazaprilat. As with the ACE prodrugs, nomutagenicity has been found, even though these drugs crossthe placenta.
(1R,3S)-Benazepril Hydrochloride Preparation Products And Raw materials
Benazepril EP Impurity B BENAZEPRIL RELATED COMPOUND G (15 MG) ((3-(1 -ETHOXYCARBONYL-3-PHENYL-(1 S)-PROPYL)AMINO-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-(3S)-BENZAZE-PINE)-1-ACETIC ACID, ETHYL ESTER) BENAZEPRIL-D5 HYDROCHLORIDE (S)-3-AMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid benazepril D-HOMOPHENYLALANINE ETHYL ESTER HYDROC& 2,3,4,5-Tetrahydro-1H-benzo[b]azepine Propitocaine hydrochloride Glycine, N-(2-ethylphenyl)-N-formyl- (9CI) 1H-1-BENZAZEPIN-3-AMINE, 2,3,4,5-TETRAHYDRO- D-β-Homophenylalanine, HPLC 98% DL-HOMOPHENYLALANINE METHYL ESTER HYDROCHLORIDE N-ISOPROPYL-AMINO-ACETIC ACID ETHYL ESTER HCL (3S)-Amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one Ethyl N-(2-butyl)glycinate (1R,3S)-Benazepril Hydrochloride 3-Amino-2,3,4,5-Tetrahydro-1H-1-benzazepin-2-one

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