ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Glycine derivative N-(1-oxohexyl)-glycine

N-(1-oxohexyl)-glycine

N-(1-oxohexyl)-glycine Basic information
Product Name:N-(1-oxohexyl)-glycine
Synonyms:Glycine, N-(1-oxohexyl)-;Hexanoylglycine;N-(1-oxohexyl)-glycine;N-caproylglycine;(Hexanol Glycine);Caproylglycine;n-Hexanoylglycine;NSC 224460
CAS:24003-67-6
MF:C8H15NO3
MW:173.21
EINECS:
Product Categories:Aliphatics;Amino Acids & Derivatives
Mol File:24003-67-6.mol
N-(1-oxohexyl)-glycine Structure
N-(1-oxohexyl)-glycine Chemical Properties
Melting point 90-92°C
Boiling point 387.2±25.0 °C(Predicted)
density 1.074±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka3.60±0.10(Predicted)
form Solid
color White to Off-White
Safety Information
MSDS Information
N-(1-oxohexyl)-glycine Usage And Synthesis
DescriptionHexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during cancer, while they are decreased 20-fold in mice following treatment with the PPARα ligand Wy 14643.
Chemical PropertiesWhite Solid
UsesAn acylaminoacid derivative as antipsychotic drug.
DefinitionChEBI: An N-acylglycine in which the acyl group is specified as hexanoyl.
N-(1-oxohexyl)-glycine Preparation Products And Raw materials
Glycine ethyl ester hydrochloride Glycine, N-coco acyl derivs., sodium salts
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