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OLEANDRIN

OLEANDRIN Basic information
Product Name:OLEANDRIN
Synonyms:FOLINERIN;OLEANDRIN;(3-beta,5-beta,16-beta)-hexopyranosyl)oxy)-14-hydroxy;(3beta,5beta,16beta)-hexopyranosyl)oxy)-14-hydroxy;14-hydroxycard-20-(22)-enolide;16-(acetyloxy)-3-((2,6-dideoxy-3-o-methyl-alpha-l-arabino-card-20(22)-enolid;6-dideoxy-3-o-methyl-l-arabino-hexopyranosyl)oxy]-16beta-(acetyloxy)-3beta-[(;corrigen
CAS:465-16-7
MF:C32H48O9
MW:576.72
EINECS:207-361-5
Product Categories:phytochemical;reference standards from Chinese medicinal herbs (TCM).;Intermediates & Fine Chemicals;chemical reagent;pharmaceutical intermediate;standardized herbal extract;Cardioglycosides & Glycosides;Pharmaceuticals
Mol File:465-16-7.mol
OLEANDRIN Structure
OLEANDRIN Chemical Properties
Melting point 250°C
alpha D25 -48.0° (c = 1.3 in methanol)
Boiling point 557.17°C (rough estimate)
density 1.26
refractive index 1.5000 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
form A solid
pka13.55±0.70(Predicted)
color Crystals from dil methanol
Safety Information
Hazard Codes T
Risk Statements 23/24/25-33-23/25
Safety Statements 22-36/37/39-45
RIDADR 2811
WGK Germany 3
RTECS FH4585000
Hazardous Substances Data465-16-7(Hazardous Substances Data)
ToxicityLD50 ivn-cat: 300 mg/kg MEIEDD 10,979,83
MSDS Information
OLEANDRIN Usage And Synthesis
Chemical PropertiesWhite to Off-White Solid
UsesCardiotonic; diuretic
DefinitionChEBI: A steroid saponin that consists of oleandrigenin having a 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl residue attached to the oxygen function at position 3.
Safety ProfilePoison by subcutaneous andintravenous routes. When heated to decomposition itemits acrid smoke and irritating fumes.
OLEANDRIN Preparation Products And Raw materials
NERIIFOLIN Poricoic acid A(F) dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate 3β-[(2,6-Dideoxy-3-O-methyl-β-D-lyxo-hexopyranosyl)oxy]-14-oxo-8,15-cyclo-14,15-seco-5β-card-20(22)-enolide ADYNERIN Pachymic acid Madecassoside 3β-[(3-O-Methyl-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-14-hydroxy-5β,14β-carda-20(22)-enolide Carboxyatractyloside 3β-[(6-Deoxy-3-O-methyl-β-D-galactopyranosyl)oxy]-14-oxo-8,15-cyclo-14,15-seco-5β-card-20(22)-enolide roburic acid Terrestrosin D Terrestrosin K (3S,5S)-2,6-Dimethyl-3,5-heptanediol OLEANDRIN, [3H]- FOLINERIN(SEE OLEANDRIN)(RG) 1,3-CYCLOPENTANEDIOL OLEANDRIN
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