N-Demethyl olanzapine

N-Demethyl olanzapine Basic information
Product Name:N-Demethyl olanzapine
Synonyms:2-Methyl-4-(1-Piperazinyl)-10H-Thieno-[2,3-b][1,5]Benzodiazepine;4'-Desmethylolanzapine;Desmethylolanzapine;LY 170055;2-METHYL-4-(1-PIPERAZINYL)-10H-THIENOL[2,3-B][1,5]BENZODIAZEPINE;10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl)-;Desmethylolanzapine dihydrochloride;Desmethylolanzapine dihydrochloride solution
CAS:161696-76-0
MF:C16H18N4S
MW:298.41
EINECS:
Product Categories:Metabolites;Olanzapine
Mol File:161696-76-0.mol
N-Demethyl olanzapine Structure
N-Demethyl olanzapine Chemical Properties
Melting point 144.5°C
Boiling point 489.2±55.0 °C(Predicted)
density 1.38±0.1 g/cm3(Predicted)
Fp 13℃
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml,Ethanol: 10 mg/ml
form A solid
pka8.58±0.10(Predicted)
Safety Information
Hazard Codes F,Xn
Risk Statements 11-20/21/22-36
Safety Statements 16-26-36/37
RIDADR UN 1648 3 / PGII
WGK Germany 2
MSDS Information
N-Demethyl olanzapine Usage And Synthesis
Chemical PropertiesBrown Solid
UsesA metabolite of Olanzapine.
DefinitionChEBI: 4'-N-desmethylolanzapine is a benzodiazepine.
General DescriptionDesmethylolanzapine is the primary metabolite of olanzapine, marketed as the atypical antipsychotic Zyprexa?for the treatment of schizophrenia and bipolar disorder. This new certified solution standard is suitable for use in LC or GC applications including clinical toxicology analysis, forensic testing, or therapeutic drug monitoring.
N-Demethyl olanzapine Preparation Products And Raw materials
Preparation ProductsOlanzapine
Methylparaben Methyl Bensulfuron methyl Parathion-methyl 2-Ethyl-4-(4-methyl-1-piperazinyl)-7-nitro-10H-thieno(2,3-b)(1,5)benzo diazepine 1-Methylpiperazine OLANZAPINE-METHYL-D3 Kresoxim-methyl N-DEMETHYLOLANZAPINE-D8 Olanzapine Thiophanate-methyl OLANZAPINE-METHYL-D3 GLUCURONIDE 1-BENZHYDRYLPIPERAZINE Flumezapine OLANZAPINE GLUCURONIDE METSULFURON METHYL 3-METHYLADENINE Tetrahydrothiophene

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