ChemicalBook Product Catalog Chemical Reagents Organic reagents Aromatic ketones 2-bromo-4-methylpropiophenone

2-bromo-4-methylpropiophenone

2-bromo-4-methylpropiophenone Basic information
Description Uses Reference
Product Name:2-bromo-4-methylpropiophenone
Synonyms:4-Methylphenyl 1-BroMoethyl Ketone;2-bromo-4-methylpropiophenone;2-bromo-1-(4-methylphenyl)propan-1-one;2-Bromo-1-(4-methylphenyl)-1-propanone;1-Propanone,2-broMo-1-(4-Methylphenyl)-;2-BROMO-4'-METHYLPROPIOPHENE;2-Bromo-1-(p-tolyl);Quality guarantee EG-2201 power
CAS:1451-82-7
MF:C10H11BrO
MW:227.1
EINECS:696-162-0
Product Categories:Medical research;Aromatics;Intermediates;Miscellaneous Reagents;organic interme;Intermediate;1451-82-7
Mol File:1451-82-7.mol
2-bromo-4-methylpropiophenone Structure
2-bromo-4-methylpropiophenone Chemical Properties
Melting point 75-77℃
Boiling point 273℃
density 1.357
Fp 59℃
storage temp. Refrigerator
solubility Soluble in chloroform and methanol.
form Solid
color White to Off-White
InChIKeyOZLUPIIIHOOPNQ-UHFFFAOYSA-N
Safety Information
Hazard Codes Xn
Risk Statements 22
HS Code 2914.79.4000
MSDS Information
2-bromo-4-methylpropiophenone Usage And Synthesis
DescriptionIt is usually used as the intermediate and raw material in the fine chemistry industry. Specifically, this chemical can act as the intermediate in the synthesis of 4-methyl methcathinone HCl, which is used as the sample for development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials.1 Moreover, this compound may function as an effective ingredient to prepare the therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives.2 In addition, this substance has been demonstrated to be involved in the preparation of a pharmaceutical composition comprising a pyrrole derivative, which shows a desirable activity for the treatment pollakiuria or urinary incontinence.3
Uses2-Bromo-4'-methylpropiophenone (cas# 1451-82-7) is a compound useful in organic synthesis.
Reference
  1. Philp, M.; Shimmon, R.; Stojanovska, N.; Tahtouh, M.; Fu, S. L., Development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials. Anal. Methods 2013, 5, 5402-5410.
  2. Alexander Wick; Jonathan Frost; Bernard Gaudilliere; Jean Bertin; Regis Dupont; Rousseau, J., Therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives. US Patent 4690931 1987.
  3. Masami Tsuda; Mitsushi Tanaka; Nakamura, A., Pyrrole derivatives and medicinal composition. US Patent 5998459 1999.
Chemical PropertiesOff-White Solid
UsesIt employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field. Also used as intermediate for 4-methylmethcathinone.
2-bromo-4-methylpropiophenone Preparation Products And Raw materials
1-BUTENE 2-Methyl-3-(3,4-methylenedioxyphenyl)propanal Potassium pyrophosphate 4-PHENYL-3-BUTYN-2-ONE Methanesulfonamide Tetrazole Pmk glycidate Indoline 3-oxo-2-phenylbutanaMide 4'-Methylpropiophenone Methyl 2-phenylacetoacetate Benzoic acid Isobutylamine C. I. Pigment White 16 (77625) Cadmium chloride Eucalyptus oil 2-bromo-3-methylpropiophenone α-Bromo-α-methylpropiophenone,2-BROMO-2-METHYLPROPIOPHENONE,A-BROMO-A-METHYLPROPIOPHENONE
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