|
| 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Basic information |
| 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Chemical Properties |
Melting point | 242-244℃ | alpha | D26 -11.7° (c = 3.9 in 0.2N NaOH) | Boiling point | 445.09°C (rough estimate) | density | 2.18 | refractive index | 1.6200 (estimate) | solubility | Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | pka | 9.56±0.50(Predicted) | form | neat | BRN | 44407 | Stability: | Hygroscopic |
| 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Usage And Synthesis |
Uses | Vicine is a pyrimidine glycosides, a precursor of the aglycons divicine and isouramil which is main factors of favism. It is found in faba/fava bean. Also, it is derived from Ethyl Glyoxylate (E918550), which is used as a reagent in the synthesis of a new class of cinnamyl-triazole compounds which can be used as selective inhibitors of human aromatase (cytochrome P 450 19A1) | Definition | ChEBI: Vicine is a glycoside. | Purification Methods | Crystallise Vicine from water (1%) or aqueous 85% EtOH, and dry it at 135o. [Bendich & Clements Biochim Biophys Acta 12 462 1953, Beilstein 31 H 163, 2 5 III/IV 4285.] |
| 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Preparation Products And Raw materials |
|