Sodium picosulfate

Sodium picosulfate Basic information
Product Name:Sodium picosulfate
Synonyms:4,4'-(2-Pyridinylmethylene)bis(phenol)bis(sulfuric acid sodium) salt;4 4'-(2-PYRIDINYLMETHYLENE) BISPHENOL BI S(HYDROGEN SULFATE )(ESTER) DISODIUM SALT;Sodium Picosulfate n -Hydrate;DA 1773;DA-1773;LA 391;C13072;Sodium Picosulfate (50 mg)
CAS:10040-45-6
MF:C18H13NO8S2.2Na
MW:481.41
EINECS:233-120-9
Product Categories:API;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Inhibitors;10040-45-6
Mol File:10040-45-6.mol
Sodium picosulfate Structure
Sodium picosulfate Chemical Properties
Melting point 283-286°C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Freely soluble in water, slightly soluble in ethanol 96 per cent.
form neat
color White to Off-White
Stability:Hygroscopic
InChIKeyGOZDTZWAMGHLDY-UHFFFAOYSA-L
Safety Information
HS Code 2933399090
Toxicitymouse,LD50,intraperitoneal,2900mg/kg (2900mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATIONBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977.
MSDS Information
Sodium picosulfate Usage And Synthesis
Chemical PropertiesOff-White Solid
OriginatorGuttalax, De Angelini, Italy ,1967
UsesSodium picosulfate acts as a stimulant laxative by increasing the frequency and the force of peristalsis and promoting electrolyte and water retention in the colon. Sodium picosulfate is most often used as laxatives.
UsesSodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.
DefinitionChEBI: Sodium picosulfate is an aryl sulfate and a member of pyridines.
Therapeutic FunctionLaxative
Sodium picosulfate Preparation Products And Raw materials
Raw materialsSodium hydroxide-->Chlorosulfonic acid-->2-Chlorophenol-->2-Pyridinecarboxaldehyde
Sodium benzoate Methyltriphenylphosphonium bromide 2-Chloro-5-chloromethylpyridine sodium 4-Methylpyridine Sodium sulfate Dichloromethylphenylsilane Diclofenac sodium Azamethiphos 2,6-Lutidine 2,4,6-Collidine Sodium citrate Sodium bicarbonate Sodium picosulfate Sodium hydroxide SODIUM PICOSULFATE IMP. B (EP): 4,4'-[(PYRIDIN-2-YL)METHYLENE]BISPHENOL Trimethylphenylammonium chloride Sodium chlorite

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