1,2-Cyclohexanedione

1,2-Cyclohexanedione Basic information
Product Name:1,2-Cyclohexanedione
Synonyms:1,2-Cyclohexanedione, 98+%;1,2-Cyclohexanedione,97%;1,2-Cyclohexanedione, 98% 10GR;Two1,2-cyclohexylketone;1,2-Cyclohexanedione 97%;1,2-Cyclohexadione;1,2-Dioxocyclohexane;1,2-CYCLOHEXANEDIONE
CAS:765-87-7
MF:C6H8O2
MW:112.13
EINECS:212-155-3
Product Categories:C3 to C6Protein Modification;Reagents for arginine modification;Carbonyl Compounds;Ketones;Specific Amino Acid Modification;Ketone;Pharmaceutical intermediate
Mol File:765-87-7.mol
1,2-Cyclohexanedione Structure
1,2-Cyclohexanedione Chemical Properties
Melting point 34-38 °C (lit.)
Boiling point 193-195 °C (lit.)
density 1,118 g/cm3
FEMA 3458 | 2-HYDROXY-2-CYCLOHEXEN-1-ONE
refractive index 1.518-1.52
Fp 184 °F
storage temp. 2-8°C
solubility Soluble in DMSO
form Liquid After Melting
color Clear yellow
Odorat 10.00 % in dipropylene glycol. sweet acorn nut skin maple caramel brothy
Odor Typenutty
Water Solubility Soluble
JECFA Number424
BRN 507419
LogP0.252 (est)
CAS DataBase Reference765-87-7(CAS DataBase Reference)
NIST Chemistry Referencec-hexane-1,2-dione(765-87-7)
EPA Substance Registry System1,2-Cyclohexanedione (765-87-7)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 22
Safety Statements 24/25
WGK Germany 3
RTECS GV0340000
8
Hazard Note Irritant
TSCA Yes
HS Code 29142990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
1,2-Cyclohexanedione Usage And Synthesis
Chemical Propertiesclear yellow liquid after melting
Uses1,2-Cyclohexanedione is utilized as a substrate to study enzyme cyclohexane-1,2-dione hydrolase, which is a new tool to degrade alicyclic compounds. It also acts as a specific reagent for arginine residues.
Uses1,2-Cyclohexanedione have been used as a substrate to study enzyme cyclohexane-1,2-dione hydrolase as a new tool to degrade alicyclic compounds.
DefinitionChEBI: Cyclohexane-1,2-dione is a cyclohexanedione carrying oxo substituents at positions 1 and 2.
Synthesis Reference(s)Journal of the American Chemical Society, 73, p. 4658, 1951 DOI: 10.1021/ja01154a048
Tetrahedron Letters, 25, p. 603, 1984 DOI: 10.1016/S0040-4039(00)99949-0
The Journal of Organic Chemistry, 39, p. 3295, 1974 DOI: 10.1021/jo00936a034
7-(BROMOMETHYL)-1,7-DIMETHYLBICYCLO[2.2.1]HEPTANE-2,3-DIONE AKOS BBS-00000233 IFLAB-BB F1052-0005 AKOS BBS-00006052 5-CHOLESTEN-3,4-DIONE 1-BROMO-7,7-DIMETHYLBICYCLO[2.2.1]HEPTANE-2,3-DIONE AKOS BBS-00001972 CAMPHORQUINONE-10-SULFONYLNORLEUCINE AKOS BBS-00002039 HEXAKETOCYCLOHEXANE OCTAHYDRATE AKOS BBS-00002007 (1S)-(+)-CAMPHORQUINONE AKOS BBS-00002008 TRIQUINOLYL 3-ALPHA-HYDROXY-6,7-DIKETOCHOLANIC ACID 4,7,7-TRIMETHYL-2,3-DIOXOBICYCLO[2.2.1]HEPTANE-1-CARBOXYLIC ACID CAMPHORQUINONE-10-SULFONIC ACID, HYDRATE 7-(IODOMETHYL)-1,7-DIMETHYLBICYCLO[2.2.1]HEPTANE-2,3-DIONE

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