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| | PYRILAMINE Basic information |
| Product Name: | PYRILAMINE | | Synonyms: | 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl-;1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridyl-;2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridin;Pyrilamine (base and/or unspecified salts);MEPYRAMINE(PYRILAMINE);2-dimethylaminoethyl-(4-methoxybenzyl)-(2-pyridyl)amine;N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine;N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine | | CAS: | 91-84-9 | | MF: | C17H23N3O | | MW: | 285.38 | | EINECS: | 202-102-2 | | Product Categories: | | | Mol File: | 91-84-9.mol |  |
| | PYRILAMINE Chemical Properties |
| Melting point | 131-132 °C | | Boiling point | bp5 201°; bp0.06 168-172° | | density | 1.0141 (rough estimate) | | refractive index | nD25 1.5760-1.5765 | | pka | pKa 4.02(H2O
t=25
c=0.002 to 0.01) (Uncertain);8.92 (Uncertain) | | Water Solubility | 3.425g/L(37.5 ºC) | | EPA Substance Registry System | Mepyramine (91-84-9) |
| | PYRILAMINE Usage And Synthesis |
| Uses | Antihistaminic. | | Uses | Pyrilamine is also used for allergy symptoms and rhinitis. | | Uses | N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain. | | Definition | ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group. | | Brand name | Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel). | | Synthesis Reference(s) | Journal of the American Chemical Society, 68, p. 1999, 1946 DOI: 10.1021/ja01214a037 | | General Description | Viscous brown liquid. | | Air & Water Reactions | May be sensitive to light. Insoluble in water. | | Reactivity Profile | PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides. | | Health Hazard | SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia. | | Fire Hazard | Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible. |
| | PYRILAMINE Preparation Products And Raw materials |
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