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| | Cefmenoxime hydrochloride Basic information |
| Product Name: | Cefmenoxime hydrochloride | | Synonyms: | 8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1);7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride;7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride;Bestcall;Bestron;Cemix;SCE-1365(free acid);Tacef | | CAS: | 75738-58-8 | | MF: | C16H18ClN9O5S3 | | MW: | 548.01 | | EINECS: | 278-299-4 | | Product Categories: | CEFMAX;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds | | Mol File: | 75738-58-8.mol |  |
| | Cefmenoxime hydrochloride Chemical Properties |
| Melting point | >175°C (dec.) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | DMSO (Slightly, Heated), Methanol (Slightly) | | form | Solid | | color | Off-White to Pale Yellow | | InChIKey | HZYJYGJIOCXOTH-AJVJENPNNA-N | | SMILES | C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NN=NN1C)(=O)O.Cl |&1:5,7,r| |
| | Cefmenoxime hydrochloride Usage And Synthesis |
| Description | Cef menoxime hydrochloride is a third generation cephalosporin antibiotic.
Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in
the 3-position; like several other compounds containing this structural element
(moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction
has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime
and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella,
Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is
relatively ineffective against Pseudomonas and Bacteroidea. | | Originator | Takeda (Japan) | | Uses | A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis. | | Uses | antibacterial | | Definition | ChEBI: The hemihydrochloride salt of cefmenoxime. | | Brand name | Cefmax (TAP);TACEF;BESTCALL. |
| | Cefmenoxime hydrochloride Preparation Products And Raw materials |
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