Menthyl isovalerate

Menthyl isovalerate Basic information
Product Name:Menthyl isovalerate
Synonyms:MENTHYL ISOVALERATE;MENTHYL ISOVALERATE, L-;FEMA 2669;Validol;Menthylisovalerat;MENTHYLISOVALERIANAT;3-Methylbutanoic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester;MENTHYL ISOVALERATE(P)
CAS:16409-46-4
MF:C15H28O2
MW:240.38
EINECS:240-460-1
Product Categories:Alphabetical Listings;Flavors and Fragrances;M-N
Mol File:16409-46-4.mol
Menthyl isovalerate Structure
Menthyl isovalerate Chemical Properties
Melting point 1.3°C (estimate)
Boiling point 260-262 °C750 mm Hg(lit.)
density 0.909 g/mL at 25 °C(lit.)
refractive index 1.4486
FEMA 2669 | MENTHYL ISOVALERATE
Fp >230 °F
Odorat 100.00 %. fruity cooling sweet woody
Odor Typefruity
optical activity[α]20/D 64°, neat
JECFA Number432
LogP5.555 (est)
EPA Substance Registry SystemButanoic acid, 3-methyl-, 5-methyl-2-(1-methylethyl)cyclohexyl ester (16409-46-4)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 2
RTECS OT0720000
MSDS Information
ProviderLanguage
SigmaAldrich English
Menthyl isovalerate Usage And Synthesis
DescriptionMenthyl isovalerate has an odor similar to both menthol and isovaleric acid, sweet and herbaceous, somewhat balsamic or root-like. It has a bitter, wood-like taste. Prepared by heating a mixture of ι-menthol and isovaleric acid at 100 - 110°C in the presence of trace concentrated H2SO4 or at 100°C in the presence of HCL.
Chemical PropertiesMenthyl isovalerate has an odor similar to both menthol and isovaleric acid, sweet and herbaceous. It has a bitter, wood like taste.
OccurrenceReported found in several peppermint essential oils: American, French, English, and Russian peppermint and nutmeg
PreparationPrepared by heating a mixture of l-menthol and isovaleric acid at 100 to 110°C in the presence of trace concentrated H2SO4 or at 100°C in the presence of HCl.
Taste threshold valuesTaste characteristics at 80 ppm: fruity, sweet, with a tutti-fruitti background.
HazardLow toxicity by ingestion and skin contact. A moderate skin contact irritant.
Menthyl isovalerate Preparation Products And Raw materials
Raw materialscarbon monoxide-->L-Menthol-->DL-Menthol-->Isovaleryl chloride-->Isobutylene-->Isovaleric acid
Methylparaben Benzyl butyrate Methyl Isoamyl nitrite (-)-Menthyl lactate Methyl 2-hydroxyethyl cellulose Parathion-methyl MENTHYL SALICYLATE 2-Butanone (2-Methoxyethyl)benzene Benzyl isobutyrate Benzyldimethylcarbinyl butyrate Dimethyl fumarate Isoamyl acetate Thiophanate-methyl Methyl salicylate Isovaleric acid Isoamyl o-hydroxybenzoate

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