2-AMINO-3-METHOXYBENZOIC ACID

2-AMINO-3-METHOXYBENZOIC ACID Basic information
Product Name:2-AMINO-3-METHOXYBENZOIC ACID
Synonyms:O-ANISIDINE-6-CARBOXYLIC ACID;2-AMINO-3-METHOXYBENZOIC ACID;2-AMINO-M-ANISIC ACID;Benzoic acid, 2-amino-3-methoxy-;2-AMINO-3-METHOXYBENZOIC ACID 99+%;3-methoxyantharanilic acid;2-azanyl-3-methoxy-benzoic acid;2-Amino-3-methoxybenzoic acid ,97%
CAS:3177-80-8
MF:C8H9NO3
MW:167.16
EINECS:
Product Categories:Phenylacetic acid;Intermediates
Mol File:3177-80-8.mol
2-AMINO-3-METHOXYBENZOIC ACID Structure
2-AMINO-3-METHOXYBENZOIC ACID Chemical Properties
Melting point 169-170 °C (lit.)
Boiling point 333.9±27.0 °C(Predicted)
density 1.303±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Powder
pka4.82±0.10(Predicted)
color White to yellow to brown
CAS DataBase Reference3177-80-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-37/39
WGK Germany 3
HS Code 29225090
MSDS Information
ProviderLanguage
SigmaAldrich English
2-AMINO-3-METHOXYBENZOIC ACID Usage And Synthesis
Chemical PropertiesWhite to light brown crystals or powder
Uses2-Amino-3-methoxybenzoic Acid is used in the preparation of CDK1/cyclin B inhibitors for application towards antitumor treatment. In addition, it is used in the synthesis of Alogliptin, an inhibitor o f dipeptidy peptidase, which aids in the lowering of blood-glucose for potential treatment of diabetes.
DefinitionChEBI: 3-methoxyanthranilic acid is an aminobenzoic acid that is anthranilic acid in which the hydrogen at position 3 is substituted by a methoxy group. It is a metabolite of kynurenine. It has a role as a mammalian metabolite. It is a member of benzoic acids and an aminobenzoic acid. It is functionally related to an anthranilic acid. It is a conjugate acid of a 3-methoxyanthranilate.
Synthesis Reference(s)The Journal of Organic Chemistry, 63, p. 6797, 1998 DOI: 10.1021/jo972158g
LABOTEST-BB LT00453594 3-(N-(TERT-BUTOXYCARBONYL)AMINO)-4-METHOXYBENZOIC ACID 3,4,5-TRIMETHOXY-2-NITROBENZOIC ACID 3-BROMO-5-METHOXY-2,6-DINITRO-BENZOIC ACID METHYL ESTER 3-BROMO-5-BENZYLOXY-2,6-DINITROBENZOIC ACID BENZYL ESTER Methyl 2-amino-3,4,5-trimethoxybenzoate 2-N-FMOC-AMINO-3-METHOXYBENZOIC ACID,FMOC-2-AMINO-3-METHOXYBENZOIC ACID METHYL 2-AMINO-5-METHOXYBENZOATE 4-Amino-2-methoxybenzoic acid sodium salt 5-CHLORO-3-METHOXY-2-NITROBENZOIC ACID BOC-2-AMINO-3-METHOXYBENZOIC ACID FMOC-2-AMINO-3,4,5-TRIMETHOXYBENZOIC ACID 458L BOC-4-AMINO-3-METHOXYBENZOIC ACID METHYL 3-METHOXY-2-NITROBENZOATE 2-(4-CHLORO-3-NITROPHENYL)-6,7,8-TRIMETHOXY-4H-3,1-BENZOXAZIN-4-ONE BOC-2-AMINO-3,4,5-TRIMETHOXYBENZOIC ACID AKOS 208-15

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