3-Hydroxypiperidine

3-Hydroxypiperidine Basic information
Product Name:3-Hydroxypiperidine
Synonyms:3-Hydroxypiperadine;3-HYDROXYPIPERIDINE;3-HYDROXYPIPERIDINE 98%;3-Hydroxypiperidine/3-Piperidinol;3-PIPERIDINOL FOR SYNTHESIS 10 G;3-Hydroxypiperidine, 98% 10GR;3-Hydroxypiperidine, 98% 50GR;3-Hydroxypiperidine, 97+%
CAS:6859-99-0
MF:C5H11NO
MW:101.15
EINECS:229-957-4
Product Categories:Pyrans, Piperidines & Piperazines;FINE Chemical & INTERMEDIATES;Alcohols and Derivatives;Pyrans, Piperidines &Piperazines;Piperidine;6859-99-0
Mol File:6859-99-0.mol
3-Hydroxypiperidine Structure
3-Hydroxypiperidine Chemical Properties
Melting point 57-61 °C
Boiling point 67-69 °C (2 mmHg)
density 1.016±0.06 g/cm3(Predicted)
Fp >100°C
storage temp. 2-8°C
solubility ethanol: 0.1 g/mL, clear
pka14.91±0.20(Predicted)
form Crystalline Powder and Lumps
color White to light yellow
PH11.5-11.7 (H2O)Aqueous solution
Water Solubility soluble
Sensitive Air Sensitive & Hygroscopic
BRN 102696
InChIKeyBIWOSRSKDCZIFM-UHFFFAOYSA-N
LogP-0.35
CAS DataBase Reference6859-99-0(CAS DataBase Reference)
Safety Information
Hazard Codes C,Xi
Risk Statements 34-20/21/22-36/37/38
Safety Statements 26-36/37/39-45-27
RIDADR UN 3263 8/PG 2
WGK Germany 3
HazardClass 8
PackingGroup III
HS Code 29333990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
3-Hydroxypiperidine Usage And Synthesis
Chemical PropertiesWhite to light yellow crystalline powder and lumps
Uses3-Hydroxypiperidine is usually used for Synthesis of unsymmetrical ureas,Synthesis of piperidine nucleoside analogs,Fluorination reactions,Synthesis of substituted pyridines.
Application3-Hydroxypiperidine may be used to synthesize the following:
2-pyrrolidinone via oxidation with iodosylbenzene
1-[2,8-bis(trifluoromethyl)quinolin-4-yl]piperidin-3-ol via reaction with 4-bromoquinoline
Reactant for:
Synthesis of unsymmetrical ureas
Synthesis of piperidine nucleoside analogs
Fluorination reactions
Synthesis of substituted pyridines
General Description3-Hydroxypiperidine can be obtained from the reduction of 3-hydroxypyridine.
SWAINSONINE (2S,4S)-N-BOC-4-HYDROXYPIPERIDINE-2-CARBO-XYLIC ACID BENZYLAMINE SALT 95% (98% E.E) tert-Butyl 4-(cyanomethyl)-4-hydroxypiperidine-1-carboxylate NALTRINDOLE HYDROCHLORIDE BETA-CHLORNALTREXAMINE DIHYDROCHLORIDE NOROXYMORPHONE PIPERIDOLATE HYDROCHLORIDE N-nitroso-3-hydroxypiperidine 3-hydroxypiperidin-2-one BETA-FUNALTREXAMINE HYDROCHLORIDE PHENCYCLIDINE-D5 HYDROCHLORIDE Ethyl 4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxypiperidine-1-carboxylate VERATRINE 3,5-Dihydroxybenzoic acid 1-Deoxynojirimycin 1-methyl-4-phenyl-4-hydroxypiperidine 3-Quinuclidinol hydrochloride NALOXONAZINE DIHYDROCHLORIDE

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