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Nilotinib 3-Imidazolyl N-oxide

Nilotinib 3-Imidazolyl N-oxide Basic information
Product Name:Nilotinib 3-Imidazolyl N-oxide
Synonyms:Nilotinib 3-Imidazolyl N-oxide;Benzamide, 4-methyl-N-[3-(4-methyl-3-oxido-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-;Nilotinib N-Oxide Impurity 1
CAS:2139382-75-3
MF:C28H22F3N7O2
MW:545.52
EINECS:
Product Categories:
Mol File:2139382-75-3.mol
Nilotinib 3-Imidazolyl N-oxide Structure
Nilotinib 3-Imidazolyl N-oxide Chemical Properties
Melting point >156°C (dec.)
density 1.39±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka12.86±0.70(Predicted)
color Pale Yellow
Safety Information
MSDS Information
Nilotinib 3-Imidazolyl N-oxide Usage And Synthesis
Uses4-Methyl-3-(4-pyridin-3-yl)pyrimidin-2-yl]amino-N-(5-(3-oxo-4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamine is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia. It is a COVID19-related research product.
Nilotinib 3-Imidazolyl N-oxide Preparation Products And Raw materials
3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamide Nilotinib impurity 3 Nilotinib Impurity 28 3-Amino-4-methylbenzoic acid Nilotinib Impurity 20 Nilotinib Impurity 1 Nilotinib genotoxic impurity 3 Nilotinib Impurity 7 Nilotinib N-Oxide Nilotinib Impurity 10 Methyl 3-amino-4-methylbenzoate Benzenamine, 3-(2-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)- 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzonitrile 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid methyl ester 1H-IMidazole, 4-Methyl-1-[3-nitro-5-(trifluoroMethyl)phenyl]- 3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate 3-(5-Methyl-1H-iMidazol-1-yl)-5-(trifluoroMethyl)benzenaMine
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