Ipodate Sodium

Ipodate Sodium Basic information
Product Name:Ipodate Sodium
Synonyms:sodiumtriiodohydrocinnamate;ipodic acid sodium salt;Ipodic acid sodium;Sodium 3-(3-{[(dimethylamino)methylene]amino}-2,4,6-triiodophenyl)propanoate;3-((dimethylaminomethylene)amino)-2,4,6-triiodo-benzenepropanoicacisodi;3-((dimethylaminomethylene)amino)-2,4,6-triiodohydrocinnamicacidsodiumsalt;3-((dimethylaminomethylene)amino)-2,4,6-triiodo-hydrocinnamicacisodiumsa;beta-(2,4,6-trijod-3-dimethylaminomethylenamino-phenyl)-propionsaeure
CAS:1221-56-3
MF:C12H14I3N2NaO2
MW:621.96
EINECS:214-945-3
Product Categories:
Mol File:1221-56-3.mol
Ipodate Sodium Structure
Ipodate Sodium Chemical Properties
Melting point 303-304° (decompn with evolution of iodine)
EPA Substance Registry SystemBenzenepropanoic acid, 3-[[(dimethylamino)methylene]amino]-2,4,6-triiodo-, sodium salt (1221-56-3)
Safety Information
HazardClass IRRITANT
ToxicityLD50 in mice (mg/kg): 290 i.v.; 2570 orally (Hoppe)
MSDS Information
Ipodate Sodium Usage And Synthesis
UsesDiagnostic aid (radiopaque medium).
UsesIpodate Sodium is used as a safe and effacacious treatment for hyperthyroidism, reducing serum T4 and T3 levels to normal amounts.
DefinitionChEBI: Ipodate Sodium is a monocarboxylic acid and a member of benzenes.
Brand nameBilivist (Berlex); Oragrafin Sodium (Bracco).
Veterinary Drugs and TreatmentsIpodate may be useful in some cats for the medical treatment of hyperthyroidism when methimazole (or carbimazole) cannot be tolerated. Because it uses a different mechanism of action than methimazole, ipodate may, potentially, be useful in reducing methimazole dosages (and hence toxicity).
Ipodate Sodium Preparation Products And Raw materials
N-Methyl 4-fluoro-2-methoxyaniline 3-Piperidin-1-ylaniline Ethanone, 1-(4-amino-3-hydroxyphenyl)- (9CI) Phenol, 3-fluoro-5-methyl- (9CI) 3-Fluoro-2-methoxyaniline 2-AMINO-5-FLUOROPHENOL Benzaldehyde, 4-amino-3-methoxy- (9CI) 1-(4-AMINO-3-METHOXYPHENYL)-1-ETHANONE Benzaldehyde, 3-fluoro-5-methoxy- (9CI) 4'-PIPERIDINOACETOPHENONE 4-FLUORO-2-METHOXYANILINE 1-ISOPROPYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID 3-[[(dimethylamino)methylene]amino]-3-(2,4,6-triiodophenyl)propionic acid 2-(ISOPROPYLAMINO)ACETOPHENONE 4-PIPERIDIN-1-YL-BENZALDEHYDE 3-(3-AMINO-2,4,6-TRIIODOPHENYL)PROPIONIC ACID Ethanone,1-(2-amino-3-methoxyphenyl)- 2-AMINO-3-FLUOROPHENOL

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