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| | Crisaborole Impurity Basic information |
| Product Name: | Crisaborole Impurity | | Synonyms: | Crisaborole Impurity;3-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]Benzonitrile;Crisaborole intermediate;5-(4-cyanophenoxy)-2-hydroxybenzoic acid;4-(3-formyl-4-hydroxyphenoxy)benzonitrile;4-((2,2'-diformyl-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile;4-(3-formyl-4-(3-formyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)phenoxy)benzonitrile;4-(3-(hydroxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile | | CAS: | 906673-42-5 | | MF: | C14H10BNO3 | | MW: | 251.05 | | EINECS: | | | Product Categories: | | | Mol File: | 906673-42-5.mol |  |
| | Crisaborole Impurity Chemical Properties |
| Melting point | 180-183°C | | Boiling point | 411.1±55.0 °C(Predicted) | | density | 1.33±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | | pka | 7.04±0.20(Predicted) | | form | Solid | | color | White to Off-White |
| | Crisaborole Impurity Usage And Synthesis |
| Uses | 5-(4-Cyanophenoxy)-2-hydroxybenzoic Acid is an impurity of Crisaborole(H947928). Crisaborole exhibits inhibitory activity against PDE4 and cytokine release. |
| | Crisaborole Impurity Preparation Products And Raw materials |
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