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| | 4-Nitrobiphenyl Basic information |
| Product Name: | 4-Nitrobiphenyl | | Synonyms: | 1-Nitro-4-phenylbenzene;1-Nitro-4-phenylbenzene, p-Phenylnitrobenzene;4-Nitrobiphenyl,98%;4-Nitrobiphenyl,99%;4-Nitrobiphenyl 100mg [92-93-3];4-(4-Nitrophenyl)benzene;NSC 1324;PARA-NITRODIPHENYL | | CAS: | 92-93-3 | | MF: | C12H9NO2 | | MW: | 199.21 | | EINECS: | 202-204-7 | | Product Categories: | Aromatics Compounds;Aromatics | | Mol File: | 92-93-3.mol |  |
| | 4-Nitrobiphenyl Chemical Properties |
| Melting point | 114 °C | | Boiling point | 340 °C | | density | 1.1919 (rough estimate) | | refractive index | 1.5880 (estimate) | | Fp | 43 °C | | solubility | Soluble in acetic acid, benzene, chloroform, and ether (Weast, 1986) | | form | Solid | | color | White | | Water Solubility | insoluble | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChI | InChI=1S/C12H9NO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H | | InChIKey | BAJQRLZAPXASRD-UHFFFAOYSA-N | | SMILES | C1(C2=CC=CC=C2)=CC=C([N+]([O-])=O)C=C1 | | CAS DataBase Reference | 92-93-3(CAS DataBase Reference) | | IARC | 3 (Vol. 4, Sup 7) 1987 | | NIST Chemistry Reference | 1,1'-Biphenyl, 4-nitro-(92-93-3) | | EPA Substance Registry System | 4-Nitrobiphenyl (92-93-3) |
| Hazard Codes | T,N | | Risk Statements | 45-51/53 | | Safety Statements | 53-45-61 | | RIDADR | 2811 | | RTECS | DV5600000 | | HazardClass | 6.1(b) | | PackingGroup | III | | HS Code | 29042090 | | Hazardous Substances Data | 92-93-3(Hazardous Substances Data) | | Toxicity | Acute oral LD50 for rats 2,230 mg/kg, rabbits 1,970 mg/kg (quoted, RTECS, 1985). |
| | 4-Nitrobiphenyl Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Chemical Properties | 4-Nitrobiphenyl exists as yellow plates or needles.. | | Uses | Formerly used as an intermediate for
4-aminobiphenyl | | Uses | Formerly in preparation of p-biphenylamine, q.v. | | Uses | 4-Nitrobiphenyl has some uses as a plasticizer, fungicide, and
wood preservative. | | Definition | ChEBI: 4-Nitrobiphenyl is a member of biphenyls. | | Synthesis Reference(s) | Tetrahedron Letters, 37, p. 4499, 1996 DOI: 10.1016/0040-4039(96)00924-0 | | General Description | White to yellow needle-like crystalline solid with a sweetish odor. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | 4-Nitrobiphenyl is incompatible with the following: Strong reducers . | | Hazard | Toxic by ingestion and skin contact. Confirmed carcinogen. | | Health Hazard | p-Nitrobiphenyl (PNB) is a
urinary bladder carcinogen in dogs. | | Safety Profile | Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data. Poison
by intraperitoneal route. Moderately toxic by
ingestion. Mutation data reported. When
heated to decomposition it emits toxic
fumes of NOx. See also NITRO
COMPOUNDS OF AROMATIC
HYDROCARBONS. | | Potential Exposure | 4-Nitrobiphenyl was formerly used in
the synthesis of 4-aminodiphenyl. It is presently used only
for research purposes; there are no commercial uses. | | Carcinogenicity | The case for the carcinogenicity of PNB
is supported by (1) the induction of urinary
bladder cancer in dogs after administration of
PNB; (2) the evidence that PNB is metabolized
in vivo to 4-aminobiphenyl (a potent carcinogen);
and (3) the possibility that the cases of
human urinary bladder cancer attributed to 4-
aminobiphenyl may also have been induced by
exposure to PNB.1 | | Shipping | UN2811 Toxic solids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required. | | Incompatibilities | Incompatible with strong reducing agents
such as hydrides, oxidizers (chlorates, nitrates, peroxides,
permanganates, perchlorates, chlorine, bromine, fluorine,
etc.); contact may cause fires or explosions. Keep away
from alkaline materials, strong bases, strong acids, oxoacids,
epoxides. | | Waste Disposal | Incineration @ 982℃/2.0 seconds
(minimum) with scrubbing for nitrogen oxides
abatement. |
| | 4-Nitrobiphenyl Preparation Products And Raw materials |
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