DIHYDROERGOTAMINE

DIHYDROERGOTAMINE Basic information
Product Name:DIHYDROERGOTAMINE
Synonyms:Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-;DIHYDROERGOTAMINE;Dihydroergotamine (base and/or unspecified salts);9,10-Dihydroergotamine;9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione;Dihydro Ergotamine Impurity 4;Levadex;DIHYDROERGOTAMINE USP/EP/BP
CAS:511-12-6
MF:C33H37N5O5
MW:583.69
EINECS:208-123-3
Product Categories:
Mol File:511-12-6.mol
DIHYDROERGOTAMINE Structure
DIHYDROERGOTAMINE Chemical Properties
Melting point 239°
alpha D20 -64°; 20546 -79° (c = 0.5 in pyridine)
Boiling point 641.14°C (rough estimate)
density 1.1992 (rough estimate)
refractive index 1.7500 (estimate)
pka9≅+-.0.60(Predicted)
Safety Information
MSDS Information
DIHYDROERGOTAMINE Usage And Synthesis
UsesAnti-adrenergic.
UsesLevadex is an intermediate in the synthesis of 2’-Epidihydroergotamine (E584910), which is an ergot alkaloid that exhibits potential neuroprotective properties against degenerative diseases.
DefinitionChEBI: Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the tr atment of migraine and orthostatic hypotension.
Brand nameD.H.E. 45 (Valeant); Migranal (Valeant) .
DIHYDROERGOTAMINE Preparation Products And Raw materials
Raw materialsergotamine
Sumatriptan ergotamine Dihydroergotamine Tartrate Bp,Eur,Ph Dihydroergotamine Mesylate USP,BP,JP,Eur,Ph DIHYDROERGOTAMINE METHANESULFONATE,Dihydroergotamine monomethanesulfonate,DIHYDROERGOTAMINE MESYLATE,DIHYDROERGOTAMINE METHANESULFONATE SALT DIHYDROERGOTAMINE TARTRATE CRYSTALLINE DIHYDROERGOTAMINE BASE DIHYDROERGOTAMINE METHANESULFONATE SALT,DIHYDROERGOTAMINE MESYLATE,DIHYDROERGOTAMINE METHANESULFONATE DIHYDROERGOTAMINE TARTRATE,DIHYDROERGOTAMINE TARTRATE SALT Dihydroergotamine for peak identification

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