De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride

De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Basic information
Product Name:De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
Synonyms:De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride;2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)acetic acid dihydrochloride;Cetirizine-3;Cetirizine EP Impurity B DiHCl (Levocetirizine Impurity 3 DiHCl);Levocetirizine Impurity 3 DiHCl (Cetirizine EP Impurity B DiHCl);Cetirizine Impurity B DiHCl;Cetirizine EP Impurity B DiHCl;Cetirizine Impurity B dihydrochloride
CAS:1000690-91-4
MF:C19H22Cl2N2O2
MW:381.3
EINECS:
Product Categories:
Mol File:1000690-91-4.mol
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Structure
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Chemical Properties
Melting point >168°C (dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Pale Beige
Safety Information
MSDS Information
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Usage And Synthesis
UsesDe(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.
De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride Preparation Products And Raw materials
4-CHLORODIPHENYLAMINE N-(2,4-Dichlorophenyl)benzenamine (R)-Cetirizine N-Oxide (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride Cetirizine Ethyl Ester (USP RC A) Cetirizine Glycerol Ester Cetirizine EP Impurity E 2(2-HYDROXYETHOXY)ACETAMIDE rac Cetirizine N-Oxide > 70% by HPLC (Mixture of Diastereomers) 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE Cetirizine EP Impurity B(base) (2-CHLORO-PHENYL)-PHENYL-AMINE Cetirizine Related Compound C Cetirizine Polyethylene Glycol (PEG) Ester Cetirizine EP Impurity F Cetirizine Methyl Ester Cetirizine Descarboxymethyl R-Isomer 2,4,6-trichloro-N-phenylaniline

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