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| | FLAVONE Basic information |
| | FLAVONE Chemical Properties |
| Melting point | 94-97 °C (lit.) | | Boiling point | 185 °C / 1mmHg | | density | 1.1404 (rough estimate) | | refractive index | 1.6600 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | solubility | >38.3 mg/mL in EtOH; >52.3 mg/mL in DMSO | | form | Crystalline Powder | | color | White | | Water Solubility | Soluble in acetone (25 mg/ml), methanol, alcohol, and chloroform. Insoluble in water. | | Merck | 14,4092 | | BRN | 157598 | | LogP | 3.560 | | CAS DataBase Reference | 525-82-6(CAS DataBase Reference) | | EPA Substance Registry System | Flavone (525-82-6) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 2 | | RTECS | DJ3100630 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29329990 |
| | FLAVONE Usage And Synthesis |
| Chemical Properties | white crystalline powder | | Uses | Flavone is a potentially useful biochemical for cytochrome P450 studies. | | Definition | One of a group of flavonoid plant pigments existing as colorless needles, that are insoluble in water and melting at 100C. It fluoresces violet in concentrated sulfuric acid. It can be synthesized. Treatment with alcoholic alkali yields flavanone. The fla | | Synthesis Reference(s) | Journal of the American Chemical Society, 79, p. 689, 1957 DOI: 10.1021/ja01560a050
The Journal of Organic Chemistry, 44, p. 497, 1979 DOI: 10.1021/jo01318a005
Tetrahedron Letters, 31, p. 4073, 1990 DOI: 10.1016/S0040-4039(00)94503-9 | | Purification Methods | Dissolve it in dilute aqueous NaOH, filter and precipitate it by adding dilute (1:1) HCl. The process is repeated twice more, and the fluorescein is dried at 100o. Alternatively, it has been crystallised from acetone by allowing the solution to evaporate at 37o in an open beaker. It has also been recrystallised from EtOH and dried in a vacuum oven. [Beilstein 19 I 721, 19 II 248, 19 III/IV 2904, 19/8 V 456.] |
| | FLAVONE Preparation Products And Raw materials |
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