ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (R)-Zanubrutinib

(R)-Zanubrutinib

(R)-Zanubrutinib Basic information
Product Name:(R)-Zanubrutinib
Synonyms:(R)-Zanubrutinib;(R)-BGB-3111;Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-7-[1-(1-oxo-2-propen-1-yl)-4-piperidinyl]-2-(4-phenoxyphenyl)-, (7R)-;Zanubrutinib Impurity 1 ((R)-Zanubrutinib);(R) Zanubrutinib,(R)Zanubrutinib;Zanubrutinib impurity-12
CAS:1691249-44-1
MF:C27H29N5O3
MW:471.55
EINECS:
Product Categories:
Mol File:1691249-44-1.mol
(R)-Zanubrutinib Structure
(R)-Zanubrutinib Chemical Properties
Boiling point 713.4±60.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 64.25 mg/mL (136.25 mM);Ethanol : < 1 mg/mL (insoluble)
pka15.35±0.40(Predicted)
Safety Information
MSDS Information
(R)-Zanubrutinib Usage And Synthesis
Uses(R)-Zanubrutinib, is the R enantiomer of Zanubrutinib, which is a selective Bruton tyrosine kinase (BTK) inhibitor.
(R)-Zanubrutinib Preparation Products And Raw materials
Ibrutinib 1-Piperidinecarboxylic acid, 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]-, 1,1-dim Propanedinitrile, 2-[hydroxy(4-phenoxyphenyl)Methylene]- Propanedinitrile, 2-[Methoxy(4-phenoxyphenyl)Methylene]- tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile tert-butyl 4-(3-cyano-2-(4-phenoxyphenyl)pyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate Pyrazolo[1,5-a]pyrimidine-3-carboxamide, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)-, (7S)- 4-ACETYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 4-PHENOXYBENZOIC ACID Ceritinib (LDK378) Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,5,6,7-tetrahydro-2-(4-phenoxyphenyl)-7-(4-piperidinyl)- Zanubrutinib
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