Sodium taurocholate

Sodium taurocholate Basic information
Product Name:Sodium taurocholate
Synonyms:2-([3-ALPHA,7-ALPHA,12-ALPHA-TRIHYDROXY-24-OXO-5-BETA-CHOLAN-24-YL]AMINO)ETHANESULFONIC ACID;ethanesulfonicacid,2-[[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24;monosodiumtaurocholicacid;n-choloyl-taurinsodiumsalt;taurocholatesodium;taurocholatesodiumsalt;5BETA-CHOLANIC ACID-3ALPHA,7ALPHA,12ALPHA-TRIOL 24-N-(2-SULFOETHYL) AMIDE SODIUM;5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
CAS:145-42-6
MF:C26H44NNaO7S
MW:537.68
EINECS:205-653-7
Product Categories:Bile Acids;Biochemistry;Steroids;145-42-6
Mol File:145-42-6.mol
Sodium taurocholate Structure
Sodium taurocholate Chemical Properties
Melting point 230 °C
alpha 23 º (c=3 H2O)
density 1.177 g/cm3(Temp: 22.5 °C)
refractive index 23 ° (C=3, H2O)
Fp 9℃
storage temp. -20°C
solubility H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow
form neat
color Brown to greenish brown
PHpH (30g/l, 25℃) : 4.5~7.5
Water Solubility > 250 g/L (20 ºC)
Decomposition 125°C
Merck 14,9075
BRN 3901620
LogP0.051 (est)
CAS DataBase Reference145-42-6(CAS DataBase Reference)
EPA Substance Registry SystemEthanesulfonic acid, 2-[[(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-, monosodium salt (145-42-6)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39-24/25
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 3
RTECS WX0400000
3-10
HS Code 29049090
Sodium taurocholate Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Usesselectively activates retinoid X receptors (RXRs)
UsesSodium taurocholate is a detergent useful for the solubilization of lipids and membrane-bound proteins.
DefinitionChEBI: Sodium taurocholate is a bile salt. It contains a taurocholate.
Purification MethodsPurify it by recrystallisation and gel chromatography using Sephadex LH-20. [Beilstein 10 III 1655, 10 IV 2078.]
Sodium taurocholate Preparation Products And Raw materials
Raw materialsCholic acid
Tauroursodeoxycholic acid Sodium sulfate Sodium benzoate Sodium acetate 1-AMINONONADECANE sodium Sodium chloride Sodium deoxycholate N-(2-MERCAPTOETHYL)ACETAMIDE Diclofenac sodium Sodium tauroglycocholate Sodium citrate Sodium taurocholate Sodium bicarbonate Sodium hydroxide Sodium chlorite Isononylamine 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Taurocholic Acid Sodium Salt

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