MEOSUC-ALA-ALA-PRO-VAL-AMC

MEOSUC-ALA-ALA-PRO-VAL-AMC Basic information

Product Name:	MEOSUC-ALA-ALA-PRO-VAL-AMC
Synonyms:	ELASTASE SUBSTRATE V;ELASTASE SUBSTRATE V, FLUOROGENIC;MEOSUC-ALA-ALA-PRO-VAL-7-AMINO-4-METHYLCOUMARIN;MEOSUC-ALA-ALA-PRO-VAL-AMC;MEOSUC-AAPV-AMC;SUC(OME)-ALA-ALA-PRO-VAL-MCA;N-METHOXYSUCCINYL-ALA-ALA-PRO-VAL 7-AMIDO-4-METHYL-COUMARIN;N-METHOXYSUCCINYL-L-ALANYL-L-ALANYL-L-PROLYL-L-VALINE 4-METHYLCOUMARYL-7-AMIDE
CAS:	72252-90-5
MF:	C31H41N5O9
MW:	627.69
EINECS:
Product Categories:	proteins;Elastase, pancreatic;Elastase, pancreaticEnzyme Substrates;Elastase, leukocyteEnzyme Substrates;Enzyme Substrates;Protease Substrates;Substrates by Enzyme
Mol File:	72252-90-5.mol

MEOSUC-ALA-ALA-PRO-VAL-AMC Chemical Properties

Boiling point	983.7±65.0 °C(Predicted)
density	1.283±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO
form	White to off-white lyophilized solid or powder
pka	13.34±0.20(Predicted)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English

MEOSUC-ALA-ALA-PRO-VAL-AMC Usage And Synthesis

Uses	Fluorogenic substrate for quantification of human leukocyte and porcine pancreatic elastase
Uses	N-Methoxysuccinyl-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin has been used as a substrate in elastase assay using bone marrow lysates and pancreatic lysates.
General Description	Sensitive fluorogenic substrate for the quantitative determination of human leukocyte (K_m = 140 μM; K_cat/K_m = 120,000 s^-1 M^-1) and porcine pancreatic elastase. Not hydrolyzed by cathepsin G. Excitation max.: ~380 nm; emission max.: ~460 nm.
Biochem/physiol Actions	Km = 140 μM; kcat/Km = 120,000 M?1 s?1as substrates for human leukocyte and porcine pancreatic elastase

MEOSUC-ALA-ALA-PRO-VAL-AMC Preparation Products And Raw materials

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