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| Product Name: | 2,4-Difluoroaniline | | Synonyms: | 2,4-difluoro-anilin;Aniline, 2,4-difluoro-;Benzenamine, 2,4-difluoro-;LABOTEST-BB LTBB000653;AKOS 91127;2,4-DIFLUOROPHENYLAMINE;2,4-DIFLUOROBENZENAMINE;1-amino-2,4-difluorobenzene | | CAS: | 367-25-9 | | MF: | C6H5F2N | | MW: | 129.11 | | EINECS: | 206-687-5 | | Product Categories: | Fluorine series;Amines;Fluorobenzene Series;pharmacetical;C2 to C6;Nitrogen Compounds;Anilines, Aromatic Amines and Nitro Compounds;Aniline;Fluorobenzene;bc0001 | | Mol File: | 367-25-9.mol |  |
| | 2,4-Difluoroaniline Chemical Properties |
| Melting point | -7.5 °C (lit.) | | Boiling point | 170 °C/753 mmHg (lit.) | | density | 1.268 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.506(lit.) | | Fp | 145 °F | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | Not miscible or difficult to mix. | | form | Liquid | | pka | 3.26±0.10(Predicted) | | Specific Gravity | 1.284 (20/4℃) | | color | Clear brown | | Water Solubility | 1-5 g/100 mL at 20.55 ºC | | Merck | 14,3147 | | BRN | 2802556 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. | | LogP | 1.7 at 25℃ and pH5-9 | | CAS DataBase Reference | 367-25-9(CAS DataBase Reference) | | NIST Chemistry Reference | 2,4-Difluoroaniline(367-25-9) | | EPA Substance Registry System | 2,4-Difluoroaniline (367-25-9) |
| | 2,4-Difluoroaniline Usage And Synthesis |
| Description | 2,4-difluoroaniline is an important intermediate used in organic synthesis, pharmaceuticals agrochemicals, dyes, and agricultural chemicals.
| | Reference | R. Garth Pews, J. A. Gall, Process and intermediates for the preparation of 2,6-difluoroaniline, Paten US5041674A
| | Chemical Properties | dark red liquid | | Uses | 2,4-Difluoroaniline is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields. | | General Description | Dark reddish-purple liquid. | | Air & Water Reactions | 2,4-Difluoroaniline may be sensitive to prolonged exposure to air. . Water soluble. | | Reactivity Profile | Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. | | Health Hazard | ACUTE/CHRONIC HAZARDS: 2,4-Difluoroaniline may be irritating to tissues. | | Fire Hazard | 2,4-Difluoroaniline is combustible. |
| | 2,4-Difluoroaniline Preparation Products And Raw materials |
| Raw materials | Iron-->Potassium fluoride-->1,3-Dichlorobenzene-->m-Phenylenediamine-->2,4-Difluoronitrobenzene | | Preparation Products | TOSUFLOXACIN TOSILATE-->TEMAFLOXACIN-->Diflufenican-->Diflunisal-->2,4,5-Trifluorobenzoic acid-->N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine-->2-Bromo-4,6-difluorophenol-->2,4-DIFLUORO-6-NITROANILINE-->2-AMINO-4,6-DIFLUOROBENZOTHIAZOLE-->Benzamide, 5-chloro-N-(2,4-difluorophenyl)-2-hydroxy--->1H-Pyrrole-3-carboxaldehyde, 1-(2,4-difluorophenyl)-2,5-dimethyl--->1-(2,4-DIFLUORO-PHENYL)-1H-PYRROLE-2-CARBALDEHYDE-->N-(2,4-DIFLUOROPHENYL)MALEAMIC ACID-->benzyl 2,4-difluoro-3-forMylphenylcarbaMate-->Acetamide, N-(2,4-difluorophenyl)-2-(hydroxyimino)- |
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