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LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE

LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Basic information
Product Name:LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
Synonyms:(DES-ARG10)-KALLIDIN;[DES-ARG9,LYS0]-BRADYKININ;H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-OH;LYS-(DES-ARG9)-BRADYKININ;LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE;LYSYL-DES-ARG9-BRADYKININ;[LYS0, DES-ARG9]-BRADYKININ;des-arg(10)-kallidi
CAS:71800-36-7
MF:C50H73N13O11
MW:1032.2
EINECS:
Product Categories:Bradykinin receptor
Mol File:71800-36-7.mol
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Structure
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Chemical Properties
density 1.45±0.1 g/cm3(Predicted)
storage temp. −20°C
form Powder
pka3.56±0.10(Predicted)
Water Solubility Soluble to 1 mg/ml in water
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Usage And Synthesis
Uses[Lys-des-Arg9]-Bradykinin has been used as a B1R agonist to investigate the role of B1R in diabetes-induced secondary hemorrhage.
Biochem/physiol Actions[Des-Arg10]-kallidin or [Lys-des-Arg9]-Bradykinin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription nuclear factor κB (NF-κB). Elevation of Lys-des[Arg9]–bradykinin because of airway inflammation in asthma patients is known to modify the immune responses. It affects the migration and production of interleukin-12 in monocyte-derived dendritic cells.
storageStore at -20°C
LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE Preparation Products And Raw materials
L-Lysine L(+)-Arginine LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE 2ACOH 4H2O H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-SER-VAL-GLN-VAL-SER-OH GLY-PHE-SER ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE MET-LYS-BRADYKININ KALLIDIN, (DES-10-ARG) [3,4-PROLYL-3,4-3H(N)]- PHE-GLY-GLY-PHE LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG,H-LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG-OH LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE H-PRO-PHE-OH LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-ARG (HUMAN, BOVINE) 3ACOH 4H2O
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