3-BUTENE-1,2-DIOL

3-BUTENE-1,2-DIOL Basic information
Product Name:3-BUTENE-1,2-DIOL
Synonyms:1,2-Dihydroxy-3-butene;1-Butene-3,4-diol;3-buten-1,2-diol;Erythrol;EPB(TM) DIOL;BUT-3-ENE-1,2-DIOL;3,4-DIHYDROXY-1-BUTENE;3-BUTENE-1,2-DIOL
CAS:497-06-3
MF:C4H8O2
MW:88.11
EINECS:207-835-1
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Acyclic;Building Blocks;Chemical Synthesis;Organic Building Blocks;Alkenes;Organic Building Blocks
Mol File:497-06-3.mol
3-BUTENE-1,2-DIOL Structure
3-BUTENE-1,2-DIOL Chemical Properties
Melting point 15.1°C (estimate)
Boiling point 195 °C/733 mmHg (lit.)
density 1.047 g/mL at 25 °C (lit.)
refractive index n20/D 1.462
Fp 222 °F
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
pka13.68±0.20(Predicted)
form Oil
color Clear Colorless
Specific Gravity1.047
BRN 1633578
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-20/21/22
Safety Statements 36
WGK Germany 3
10
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
3-BUTENE-1,2-DIOL Usage And Synthesis
Chemical Propertiesclear colorless liquid
UsesDecomposition product of Erythritol.
Uses3,4-Dihydroxy-1-butene can be used:
  • As a reactant to synthesize cyclic organic carbonates by continuous flow procedure.
  • To prepare substituted oxazolidinone ligands used to target medicinally relevant RNAs.

General Description3,4-Dihydroxy-1-butene, also known as 3-butene-1,2-diol (BDdiol), is a metabolite of 1,3-butadiene. It forms the precursor for synthesizing different chiral building blocks. BDdiol can undergo oxidation to form hydroxymethylvinyl ketone (HMVK). 1,2-epoxy-3-butene (EB) on hydrolysis in the presence of epoxide hydrolases (EH) forms BDdiol.
3-BUTENE-1,2-DIOL Preparation Products And Raw materials
Preparation Products3-Buten-2-one, 1-hydroxy-
ETHYL 4,6-DI-O-ACETYL-2,3-DIDEOXY-ALPHA-D-ERYTHRO-HEX-2-ENOPYRANOSIDE HEXA-O-ACETYL-LACTAL BROMOCONDURITOL Erythorbic Acid Ascorbyl Palmitate picromycin GARDENOSIDE HEMATEIN 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE METHYL 2,5-DIHYDRO-2,5-DIMETHOXY-2-FURANCARBOXYLATE D-Galactal (+)-5,6-O-Isopropylidene-L-ascorbic acid Harpagoside (-)-TETRA-O-BENZOYL-2-HYDROXY-D-GLUCAL Pseudouridine 1,6-DIPHENYL-1,5-HEXADIENE-3,4-DIOL CIS-(1S,2R)-3-METHYL-3,5-CYCLOHEXADIENE-1,2- DIOL 2,3,4,5-TETRA-O-ACETYL-1-DEOXY-D-ARABINO-HEX-1-ENOPYRANOSE,

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