1,8-Diamino-3,6-dioxaoctane

1,8-Diamino-3,6-dioxaoctane Basic information
Product Name:1,8-Diamino-3,6-dioxaoctane
Synonyms:2,2’-[1,2-ethanediylbis(oxy)bis-ethanamin;1,8-DIAMINO-3,6-DIOXAOCTANE;NSC 28972;1,8-Diamino-3,6-dioxaoctane Ethylene Glycol Bis(2-aminoethyl) Ether;1,8-DiaMino-3,6-dioxaoCLane;1,8-DIAMINO-3,6-DIOXAOCTANE FOR SYNTHESI;2-[2-(2-AMino-ethoxy)-ethoxy]-ethylaMine;1,8-Diamino-3,6-dioxaoctane, 2,2'-(Ethylenedioxy)diethylamine, 1,2-Bis(2-aminoethoxy)ethane
CAS:929-59-9
MF:C6H16N2O2
MW:148.2
EINECS:213-203-6
Product Categories:Aliphatics;Amines;PROTAC LINKER;peg
Mol File:929-59-9.mol
1,8-Diamino-3,6-dioxaoctane Structure
1,8-Diamino-3,6-dioxaoctane Chemical Properties
Boiling point 105-109 °C6 mm Hg(lit.)
density 1.015 g/mL at 25 °C(lit.)
vapor pressure 71Pa at 20℃
refractive index n20/D 1.461(lit.)
Fp >230 °F
storage temp. Store below +30°C.
solubility soluble in Dimethylformamide, Methanol
form Liquid
pka9.04±0.10(Predicted)
color Colorless to Almost colorless
Water Solubility Soluble in 0.4 parts water.
Sensitive Hygroscopic
BRN 1739187
CAS DataBase Reference929-59-9(CAS DataBase Reference)
EPA Substance Registry SystemEthanamine, 2,2'-[1,2-ethanediylbis(oxy)]bis- (929-59-9)
Safety Information
Hazard Codes C
Risk Statements 22-34-42/43-37
Safety Statements 23-26-36/37/39-45
RIDADR UN 2735 8/PG 2
WGK Germany 3
34
TSCA Yes
HazardClass 8
PackingGroup III
HS Code 29221990
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
1,8-Diamino-3,6-dioxaoctane Usage And Synthesis
DescriptionAmino-PEG2-Amine is a crosslinker containing two amino groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
Chemical PropertiesCLEAR COLOURLESS LIQUID
Uses2,2'-(Ethylenedioxy)bis(ethylamine) is used to linker to form conjugates of manganese-doped zinc sulfide nanoparticles with folic acid.
Application1,8-Diamino-3,6-dioxaoctane is a chelating agent that has been shown to have antibacterial efficacy against gram-positive bacteria. It has been demonstrated to bind to a variety of functionalities such as amines, low energy metals, and hydroxy groups. It has been studied in the synthesis of coordination complexes with a range of geometric structures. The synthesis methods for this compound include solid-phase synthesis and hydrolysis of ethylenediamine. This compound has also been used as an electron donor in fluorescence techniques and morphology studies.
DefinitionChEBI: Ethylene glycol bis(2-aminoethyl) ether is an ether.
Flammability and ExplosibilityNotclassified
KRYPTOFIX 22 DD 4-Nitrophenyl 2-Acetamido-6-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl) -3-O-(b-D-galactopyranosyl)-2-deoxy-a- D-galactopyranoside 4-METHYLUMBELLIFERYL-N,N',N''-TRIACETYL-BETA-CHITOTRIOSIDE Kryptofix 222 2,2'-BIS(2-OXAZOLINE) N,N'-DIBENZYL-1,4,10,13-TETRAOXA-7,16-DIAZACYCLOOCTADECANE ETH 1001 KRYPTOFIX(R) 211 KRYPTOFIX 221D KRYPTOFIX 23 5,6,14,15-DIBENZO-4,7,13,16,21,24-HEXAOXA-1,10-DIAZABICYCLO[8.8.8]HEXACOSANE N(1)-biotinyl-N(8)-(cGMP-succinyl)-1,8-diamino-3,6-dioxaoctane 5,6-BENZO-4,7,13,16,21,24-HEXAOXA-1,10-DIAZABICYCLO[8.8.8]HEXACOS-5-ENE 1,8-Diamino-3,6-dioxaoctane KRYPTOFIX(R) 221 Iminodiacetonitrile DIHYDROSTREPTOMYCIN SESQUISULFATE SALT P-NITROPHENYL BETA-D-N,N',N''-TRIACETYLCHITOTRIOSE

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