1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE

1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE Basic information
Product Name:1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
Synonyms:CYCLEN-4HCL;CYCLEN TETRAHYDROCHLORIDE;1,4,7,10-Tetraazacyclododecane tetrahydrochloride, 97+%;1,4,7,10-Tetraazacyclododecane (Cyclen) tetrahydrochloride;Cyclen tetrahydrochloride,98%;1,4,7,10-Tetraazacyclododecane,hydrochloride;1,4,7,10-Tetraazacyclododecane, hydrochloride(1:4);1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE
CAS:10045-25-7
MF:C8H21ClN4
MW:208.73
EINECS:
Product Categories:Analytical Chemistry;Azacrown Ethers;Crown Ethers;Functional Materials;Ligands for Pharmaceutical Research;Macrocycles for Host-Guest Chemistry;Magnetic Resonance Imaging (Chelating Reagents);Ring Systems
Mol File:10045-25-7.mol
1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE Structure
1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE Chemical Properties
Melting point 297-300 °C
storage temp. Inert atmosphere,Room Temperature
form Crystalline Solid
color White
Sensitive Hygroscopic
CAS DataBase Reference10045-25-7(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
RTECS XA5253000
10-21
HazardClass 9
HazardClass IRRITANT, MOISTURE SENSITIVE
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE Usage And Synthesis
Chemical Propertieswhite crystalline solid
UsesCyclen tetrahydrochloride may be used for the synthesis of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methyleneethylphosphinic acid), a new macrocyclic polyaza polyphosphinate ligand. It may also be used in the synthesis of anthraquinone-pendant cyclen.
General DescriptionCyclen tetrahydrochloride is a macrocycle hydrochloride salt. It can be synthesized using perhydro-2a,4a,6a,8a-tetraazacyclopenteno[1,3-f,g]acenaphthylene as a precursor. Cyclen tetrahydrochloride has an orthorhombic crystal structure. Cations are reported to exhibit crystallographic two-fold rotation symmetry and [3333] quadrangular conformation, having protonated N atoms at corner positions. Synthesis of cyclen from the corresponding butanedione-protected linear tetramines has been reported.
1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE Preparation Products And Raw materials
Preparation ProductsCyclen
Cyclen CYCLODODECANE 1-(2-(5-(DIMETHYLAMINO)-1-NAPTHALENESULFONAMIDO)ETHYL)-1,4,7,10-TETRAAZACYCLODODECANE, TETRAHYDROCHLORIDE, DIHYDRATE 1,4,7,10-TETRAAZACYCLODODECANE TETRAHYDROCHLORIDE 1,1'-[1,2-PHENYLENEBIS-(METHYLENE)]-BIS-(1,4,7,10-TETRAAZACYCLODODECANE) OCTAHYDROCHLORIDE 1,1'-[1,3-PHENYLENEBIS-(METHYLENE)]-BIS-(1,4,7,10-TETRAAZACYCLODODECANE) OCTAHYDROCHLORIDE 12-Crown-4 1,1'-[1,4-PHENYLENEBIS-(METHYLENE)]-BIS-(1,4,7,10-TETRAAZACYCLODODECANE) OCTAHYDROCHLORIDE

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