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| | 2',3'-O-Isopropylideneguanosine Basic information |
| Product Name: | 2',3'-O-Isopropylideneguanosine | | Synonyms: | 2',3'-ISOPROPYLIDENE-GUANOSINE;2',3'-O-Isopropylideneguano;-O-Isopropylideneguanosine;2',3'-O-ISOPROPYLIDENE-GUANOSINE;9-(2,3-O-Isopropylidene-beta-D-ribofuranosyl)guanine;2',3'-O-Isopropylidene-D-guanosine;9-[(3aR,4R,6R,6aR)-2,2-dimethyl-4-methylol-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one;9-[(3aR,4R,6R,6aR)-4-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]-2-amino-3H-purin-6-one | | CAS: | 362-76-5 | | MF: | C13H17N5O5 | | MW: | 323.3 | | EINECS: | 206-651-9 | | Product Categories: | Biochemistry;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Nucleotides;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides | | Mol File: | 362-76-5.mol |  |
| | 2',3'-O-Isopropylideneguanosine Chemical Properties |
| Melting point | 296 °C | | density | 1.93±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMSO, 15% Ammonium Hydroxide, Hot 50% aq. Ethanol, Methanol, Warm Water | | form | Solid | | pka | 9?+-.0.20(Predicted) | | color | White to Off-White | | InChI | InChI=1S/C13H17N5O5/c1-13(2)22-7-5(3-19)21-11(8(7)23-13)18-4-15-6-9(18)16-12(14)17-10(6)20/h4-5,7-8,11,19H,3H2,1-2H3,(H3,14,16,17,20)/t5-,7-,8-,11-/m1/s1 | | InChIKey | XKPDAYWPKILAMO-IOSLPCCCSA-N | | SMILES | OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@@H]2OC(O[C@H]12)(C)C | | CAS DataBase Reference | 362-76-5(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29349990 |
| | 2',3'-O-Isopropylideneguanosine Usage And Synthesis |
| Chemical Properties | White Crystalline Solid | | Uses | A useful precursor for the preparation of nucleic acids. | | Uses | 2',3'-O-Isopropylideneguanosine is a useful precursor for the preparation of nucleic acids
| | Synthesis |
Add 10 mL of anhydrous pyridine to 2 g (7.45 mmol) of solid 2',3'-O-Isopropylideneguanosine to form a white suspension.
1 Remove the pyridine under reduced pressure to remove any trapped water;
2 Repeat the previous step;
3 Add 5 mL of acetone to the residue and stir for 30 minutes;
4 Add 50 mL of ether to the mixture and stir for 1 hour;
5 Filter the resulting precipitate and wash it with ether;
6 Dry the product in a vacuum desiccator over P2O5.
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| | 2',3'-O-Isopropylideneguanosine Preparation Products And Raw materials |
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