ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives FMOC-amino acid FMOC-6-AMINOHEXANOIC ACID

FMOC-6-AMINOHEXANOIC ACID

FMOC-6-AMINOHEXANOIC ACID Basic information
Product Name:FMOC-6-AMINOHEXANOIC ACID
Synonyms:FMOC-NH-(CH2)5-COOH;FMOC-AMINOCAPROIC ACID;FMOC-AHX(6)-OH;FMOC-ACP-OH;FMOC-ACP(6)-OH;FMOC-6-ACA-OH;FMOC-6-AHX-OH;FMOC-6-AMINOCAPROIC ACID
CAS:88574-06-5
MF:C21H23NO4
MW:353.41
EINECS:
Product Categories:Unusual Amino Acids;Amino Acid Derivatives;Amino Acids
Mol File:88574-06-5.mol
FMOC-6-AMINOHEXANOIC ACID Structure
FMOC-6-AMINOHEXANOIC ACID Chemical Properties
Melting point 114 °C
Boiling point 582.7±33.0 °C(Predicted)
density 1.210±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in water or 1% acetic acid
pka4.75±0.10(Predicted)
form Powder
color White
Water Solubility Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble.
BRN 5883220
CAS DataBase Reference88574-06-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 3
HS Code 2924 29 70
HazardClass IRRITANT
MSDS Information
ProviderLanguage
SigmaAldrich English
FMOC-6-AMINOHEXANOIC ACID Usage And Synthesis
DescriptionFmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical PropertiesWhite powder
UsesFmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry.
FMOC-6-AMINOHEXANOIC ACID Preparation Products And Raw materials
Preparation Products6-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)hexanoic acid
3-(1-FMOC-PIPERIDIN-4-YL)-PROPIONIC ACID ACA FMOC-6-AMINOHEXANOIC ACID N-HYDROXYSUCCINIMIDE ESTER Fmoc-L-beta-homoproline FMOC-6-AMINOHEXANOIC ACID-SASRIN(TM)-RESIN,FMOC-6-AMINOHEXANOIC ACID-P-ALKOXYBENZYL ALCOHOL RESIN FMOC-CIS-1,4-AMINOCYCLOHEXYL ACETIC ACID FMOC-TRANEXAMIC ACID N,N'-Bis[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-lysine pentafluorophenyl ester N-α,N-ε-di-Fmoc-D-lysine N-Boc-N'-Fmoc-D-lysine Fmoc-6-Aminohexanoic acid-Wang Resin (100-200 mesh, 1% DVB) FMOC-6-AMINOHEXANOIC ACID H-D-LYS(FMOC)-OH DDE-LYS(FMOC)-OH FMOC-LYS(FMOC)-OH H-LYS(ME3)-OH HCL FMOC-(+/-)-CIS-3-AMINOCYCLOHEXANE-1-CARBOXYLIC ACID N-Boc-N'-Fmoc-L-Lysine
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