2-Fluoro-6-Chlorobenzonitrile

2-Fluoro-6-Chlorobenzonitrile Basic information
Synthesis
Product Name: 2-Fluoro-6-Chlorobenzonitrile
Synonyms:AKOS BBS-00006480;LABOTEST-BB LT00159627;2-CHLORO-6-FLUOROBENZONITRILE;6-Chloro-2-Fluorobenzonitrile;2-CHLORO-6-FLUOROBENZONITRILE 99% (H&;2-Chloro-6-fluorobenzonitrile 98%;2-Chloro-6-fluorobenzonitrile98%;2-fluoro-6-chlorophenyl carbonitrile
CAS:668-45-1
MF:C7H3ClFN
MW:155.56
EINECS:211-571-2
Product Categories:Fluorine series;Pyridines;Aromatic Nitriles;C6 to C7;Cyanides/Nitriles;Nitrogen Compounds;Benzene nitrile;Chlorine Compounds;Fluorine Compounds;Nitriles
Mol File:668-45-1.mol
	2-Fluoro-6-Chlorobenzonitrile Structure
2-Fluoro-6-Chlorobenzonitrile Chemical Properties
Melting point 55-59 °C(lit.)
Boiling point 104 °C11 mm Hg(lit.)
density 1.3760 (estimate)
Fp 104-105°C/11mm
storage temp. Sealed in dry,Room Temperature
Water Solubility Insoluble in water
form powder to crystal
color White to Light yellow
BRN 1940332
CAS DataBase Reference668-45-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,T,Xi
Risk Statements 20/21/22-36/37/38
Safety Statements 26-37/39-36/37/39-36
RIDADR UN 3439 6.1/PG 3
WGK Germany 3
Hazard Note Toxic
HazardClass 6.1
PackingGroup III
HS Code 29269095
MSDS Information
ProviderLanguage
2-Chloro-6-fluorobenzonitrile English
SigmaAldrich English
ACROS English
ALFA English
2-Fluoro-6-Chlorobenzonitrile Usage And Synthesis
SynthesisA further example of nitro rather than chloro acting as a leaving group is demonstrated in the reaction of Ph4PHF2 with 2-chloro-6-nitrobenzonitrile to give 2-fluoro-6- chlorobenzonitrile.
2-Fluoro-6-Chlorobenzonitrile
Chemical Propertiescolourless to light beige crystals, crystalline
Uses2-Chloro-6-fluorobenzonitrile was used in the synthesis of:
  • rac-2-chloro-6-(oxiran-2-ylmethoxy)benzonitrile
  • high-molecular-weight, soluble polyarylether alternating copolymers containing pendent cyano groups
General Description2-Chloro-6-fluorobenzonitrile is an inhibitor of cellulose synthesis.
2-Fluoro-6-Chlorobenzonitrile Preparation Products And Raw materials
Raw materials2-CHLORO-6-NITROBENZONITRILE
Preparation Products5-METHOXY-QUINAZOLIN-4-YLAMINE-->2-CHLORO-6-FLUOROBENZYLAMINE-->2-Chloro-6-mercapto benzonitrile-->3-bromo-2-chloro-6-fluorobenzonitrile
6-CHLORO-2-FLUORO-3-METHYLBENZONITRILE Tetrachloroterephthalonitrile 2-CHLORO-6-FLUORO-3-METHOXYBENZONITRILE Transfluthrin Chlorothalonil 2-CHLORO-3,6-DIFLUOROBENZONITRILE 2-Fluorobenzonitrile 2-CHLORO-6-FLUORO-3-METHYLBENZONITRILE 3,6-DICHLORO-2-FLUOROBENZONITRILE Difluorochloromethane 2-Fluoro-6-Chlorobenzonitrile 2-Chloro-6-fluorophenol 2-CHLORO-6-FLUORO-3-NITROBENZONITRILE 1,2-Difluorobenzene 2,4-Dichloro-3-fluorobenzonitrile 4-Chloro-2-fluorobenzonitrile Florfenicol 2,3-DICHLORO-6-FLUOROBENZONITRILE

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