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| | Steviol Basic information |
| Product Name: | Steviol | | Synonyms: | Steviol glycoside with 80-95% stevioside;STEVIOL(P);Steviol hydrate
;ent-13-Hydroxykauran-16-en-19-oic acid;NSC 226902;Kaur-16-en-18-oic acid,13-hydroxy-, (4a)-;Steviol, 98%, from Stevia rebaudiana;Stevioside 471-80-7 | | CAS: | 471-80-7 | | MF: | C20H30O3 | | MW: | 318.45 | | EINECS: | | | Product Categories: | standard substance;reagent;Natural Plant Extract | | Mol File: | 471-80-7.mol |  |
| | Steviol Chemical Properties |
| Melting point | 215° | | alpha | D -94.7° | | Boiling point | 464.5±45.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,2-8°C | | solubility | DMSO: >10mg/mL | | form | powder | | pka | 4.65±0.60(Predicted) | | color | white to tan | | Stability: | Light Sensitive | | InChIKey | QFVOYBUQQBFCRH-ZPNQOMQUSA-N | | LogP | 4.035 (est) |
| WGK Germany | 3 | | RTECS | NZ8176000 | | HS Code | 29181990 |
| | Steviol Usage And Synthesis |
| Uses | Has been proposed as non-nutritive sweetening agent. | | Uses | Steviol is an aglycone of the natural sweetener Stevioside (90%, S686730) and is found to be highly mutagenic compared to Stevioside. | | Definition | ChEBI: Steviol is an ent-kaurane diterpenoid that is 5beta,8alpha,9beta,10alpha-kaur-16-en-18-oic acid in which the hydrogen at position 13 has been replaced by a hydroxy group. It has a role as an antineoplastic agent. It is a tetracyclic diterpenoid, a tertiary allylic alcohol, a monocarboxylic acid, a bridged compound and an ent-kaurane diterpenoid. It is a conjugate acid of a steviol(1-). | | Health Hazard | Steviol has been reported to be mutagenic.Wide use of stevia in Japan for >30 years did not produce any known deleterious side effects. In Japan, enzymatically glycosylated blend of stevioside and rebaudioside A, which appears to impart a cleaner taste profile, is also available commercially. | | Biochem/physiol Actions | Steviol is an inhibitor of hOAT1 and hOAT3 organic anion transporters. Human organic anion transporter hOAT1 belongs to a superfamily of organic anion transporters, which play critical roles in the body disposition of clinically important drugs including anti-HIV therapeutics, anti-tumor drugs, antibiotics, anti-hypertensives, and anti-inflammatories. Steviol is a useful tool for studying renal drug clearance. |
| | Steviol Preparation Products And Raw materials |
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