Posaconazole Impurity 48

Posaconazole Impurity 48 Basic information
Product Name:Posaconazole Impurity 48
Synonyms:4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl);posaconazole N-Oxide impurity 3;Posaconazole Impurity 48;Posaconazole 1-Oxido Impurity;D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-4-oxido-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-;4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazine 1-oxide;4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazine 1-oxide (Posaconazole Impurity);Posaconazole Piperazine N4-Oxide
CAS:1902954-03-3
MF:C37H42F2N8O5
MW:716.79
EINECS:
Product Categories:
Mol File:1902954-03-3.mol
Posaconazole Impurity 48 Structure
Posaconazole Impurity 48 Chemical Properties
solubility Chloroform (Slightly), Methanol (Slightly)
pka14.72±0.20(Predicted)
form Solid
color Off-White
Safety Information
MSDS Information
Posaconazole Impurity 48 Usage And Synthesis
UsesPosaconazole Mono N-Oxide is a degradation product of Posaconazole (P689600), which is an orally active triazole antifungal.
Posaconazole Impurity 48 Preparation Products And Raw materials
Posaconazole-d5 1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]- Posaconazole DiastereoisoMer interMediate 2 Posaconazole Impurity 17 Posaconazole Impurity 44 Posaconazole Impurity 49 Posaconazole-d4 Posaconazole Diastereoisomer 12 1,3-PROPANEDIOL, 2-[2-(2,4-DIFLUOROPHENYL)-2-PROPEN-1-YL]- D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-(1-ethylpropyl)-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]Methyl]-1-(1H-1,2,4-triazol-1-yl)- Posaconazole Impurity 50 Posaconazole Impurity 25 Posaconazole Impurity 42 Posaconazole Impurity 47 D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-(hydroxyMethyl)-1-(1H-1,2,4-triazol-1-yl)- Posaconazole iMpurity 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one Posaconazole Diastereoisomer 13

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