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| | Sodium diethyldithiocarbamate trihydrate Basic information |
| | Sodium diethyldithiocarbamate trihydrate Chemical Properties |
| Melting point | 95-98.5 °C(lit.) | | density | 1.100 | | vapor density | 5.9 (vs air) | | storage temp. | room temp | | solubility | H2O: passes test | | form | Crystals or Powder | | color | White to off-white | | PH | 7 (20g/l, H2O, 20℃) | | Odor | Odorless | | PH Range | 11.6 | | Water Solubility | FREELY SOLUBLE | | Sensitive | Hygroscopic | | Merck | 14,3378 | | BRN | 3920507 | | Stability: | Stable. Incompatible with strong oxidizing agents. Hygroscopic. | | CAS DataBase Reference | 20624-25-3(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-38-41-36/37/38 | | Safety Statements | 26-39-37/39-36 | | RIDADR | UN 3077 9 / PGIII | | WGK Germany | 3 | | RTECS | EZ6550000 | | TSCA | Yes | | HS Code | 29302000 | | Toxicity | LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rat > 1000 mg/kg |
| | Sodium diethyldithiocarbamate trihydrate Usage And Synthesis |
| Chemical Properties | white to light yellow crystals | | Uses | A possible nuclear factor kappa B inhibitor. | | Uses | Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. Sodium diethyldithiocarbamate trihydrate is a copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
| | Uses | Sodium diethyldithiocarbamate trihydrate is a spin trapping reagent used in conjunction with ferrous ion to detect nitric oxide in brain, kidney, liver and other tissues. It is used as sensitive reagent for the determination of copper, rubber vulcanization accelerator and finds application in the determination of other metals such as zinc, cobalt, platinum and palladium. Furthermore, it is an inhibitor of superoxide dismutase, ascorbate oxidase and other enzymes as well as inhibits the induction of macrophage nitric oxide synthase. | | General Description | Sodium diethyldithiocarbamate trihydrate may be used:
- To synthesize cis-dichlorobis(N,N-diethyldithiocarbamato) tin(IV) by reacting with tin(II) chloride.
- As an alternative to xanthates to generate carbamoyl radical precursors.
- To synthesize a soluble precursor polymer for poly(thienylene vinylene).
- To synthesize dichlorotetrakis(dimethyl sulfoxide)ruthenium (II), which can be a precursor to prepare other ruthenium complexes.[17}
| | Biochem/physiol Actions | Inhibits induction of macrophage nitric oxide synthase. | | Purification Methods | Recrystallise it from water. [Beilstein 4 III 224, 4 IV 390.] |
| | Sodium diethyldithiocarbamate trihydrate Preparation Products And Raw materials |
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