O-DesmethylApixabanSulphateNa

O-DesmethylApixabanSulphateNa Basic information
Product Name:O-DesmethylApixabanSulphateNa
Synonyms:O-DesmethylApixabanSulphateNa;Apixaban Impurity 105;4,5,6,7-Tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 4,5,6,7-tetrahydro-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1-[4-(sulfooxy)phenyl]-;Apixaban Impurity 242
CAS:1118765-14-2
MF:C24H23N5O7S
MW:525.53
EINECS:
Product Categories:
Mol File:1118765-14-2.mol
O-DesmethylApixabanSulphateNa Structure
O-DesmethylApixabanSulphateNa Chemical Properties
density 1.61±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka-4.98±0.18(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
MSDS Information
O-DesmethylApixabanSulphateNa Usage And Synthesis
UsesO-Desmethyl Apixaban Sulfate is an impurity of Apixaban (A726700), is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
O-DesmethylApixabanSulphateNa Preparation Products And Raw materials
Apixaban-13C-D3 Apixaban Impurity 15 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one Apixaban Impurity 102 Apixaban Impurity 22 2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE Apixaban Impurity 7 Apixaban Impurity 51 1-(4-Methoxyphenyl)-6-(4-iodophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-, 2-hydroxy-1-methylethyl ester 4-Pyridineacetic acid, 1,2,5,6-tetrahydro-3-hydroxy-α,2-dioxo-1-[4-(2-oxo-1-piperidinyl)phenyl]- Apixaban Impurity 8 Hydroxy O-Desmethyl Apixaban ethyl (E)-2-(2-(4-methoxyphenyl)hydrazono)propanoate Apixaban Impurity 24 Apixaban-d3 Apixaban Impurity 52 Hydroxy O-Desmethyl Apixaban Sulfate

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