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2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid

2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Basic information
Product Name:2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
Synonyms:2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat Impurity 18/Febuxostat Isopropyl Ether Analog/2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid;Febuxostat-11;Febuxostat Isopropoxy Acid (J);5-Thiazolecarboxylic acid, 2-[3-cyano-4-(1-methylethoxy)phenyl]-4-methyl-
CAS:144060-52-6
MF:C15H14N2O3S
MW:302.35
EINECS:
Product Categories:
Mol File:144060-52-6.mol
2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Structure
2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Chemical Properties
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White
Safety Information
MSDS Information
2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Usage And Synthesis
UsesFebuxostat Isopropyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.
2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid Preparation Products And Raw materials
4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate FeBuxostat Impurity 26 FeBuxostat Impurity 33 Febuxostat impurity 37 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl 2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5- carboxylate FeBuxostat Impurity 18 ethyl 2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5- carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 14 Febuxostat Bromo Impurity 2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid FeBuxostat Impurity 32 ethyl 2-(4-butoxy-3-formylphenyl)-4-methylthiazole-5- carboxylate 2-(4-HYDROXY-PHENYL)-4-METHYL-THIAZOLE-5-CARBOXYLIC ACID Febuxostat impurity 36
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