2,4-Dichloro-6,7-dimethoxyquinazoline

2,4-Dichloro-6,7-dimethoxyquinazoline Basic information
Product Name:2,4-Dichloro-6,7-dimethoxyquinazoline
Synonyms:TIMTEC-BB SBB000972;2,4-DICHLORO-6,7-DIMETHOXYQUINAZOLINE;2,4-Dichloro-6,7-dimethoxyquin;Doxazosin Impurity 5(Doxazosin EP Impurity E);Doxazosin Impurity 6;2-Chloro-6,7-diMethoxyquinazolin-4-yl Chloride;2,4-Dichloro-6-Methoxy-7-quinazolinyl Methyl ether;Doxazosin Related Compound E (20 mg) (2,4-dichloro-6,7-dimethoxyquinazoline)
CAS:27631-29-4
MF:C10H8Cl2N2O2
MW:259.09
EINECS:608-117-4
Product Categories:Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Quinazolines;QuinazolinesHeterocyclic Building Blocks;Aromatics;Heterocycles series;Quinolines, Quinazolines and derivatives;Quinoline&Isoquinoline;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:27631-29-4.mol
2,4-Dichloro-6,7-dimethoxyquinazoline Structure
2,4-Dichloro-6,7-dimethoxyquinazoline Chemical Properties
Melting point 175-178 °C (lit.)
Boiling point 340.5±42.0 °C(Predicted)
density 1.5369 (rough estimate)
refractive index 1.6100 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka-0.49±0.30(Predicted)
form Crystalline Powder
color Pale yellow to beige
Water Solubility Insoluble in water.
Sensitive Moisture Sensitive
BRN 190331
CAS DataBase Reference27631-29-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26-36
WGK Germany 3
HS Code 29334900
MSDS Information
ProviderLanguage
ACROS English
ALFA English
2,4-Dichloro-6,7-dimethoxyquinazoline Usage And Synthesis
Chemical Propertiespale yellow to beige crystalline powder
UsesAn intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. An intermediate in the preparation of Terazosin (T105000).
Uses2,4-Dichloro-6,7-dimethoxyquinazoline is used as an intermediate in the preparation of potential inhibitors of epidermal growth factor receptor kinases. It is also used as an intermediate in the preparation of terazosin.
2,4-Dichloro-6,7-dimethoxyquinazoline Preparation Products And Raw materials
4-Chloro-7-methoxyquinazoline Metformin Primaquine diphosphate 2-CHLORO-6,7-DIMETHOXYQUINAZOLINE 4-CHLORO-6-HYDROXYQUINAZOLINE 2-Chloroquinazoline 6-Quinazolinol (6CI,7CI,8CI,9CI) Sulfaquinoxaline 2-CHLORO-7-METHOXYQUINAZOLINE Dimethyldimethoxysilane 2-Chloropyrimidine 4-CHLORO-7-HYDROXYQUINAZOLINE 2,4-Dichloro-6,7-dimethoxyquinazoline 2,4-Dichloro-7-methoxyquinazoline Quinazoline Dimethyl carbonate 4-CHLORO-QUINAZOLINE 2,4-Dichloroquinazoline

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