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Ezetimibe Related Impurity 37

Ezetimibe Related Impurity 37 Basic information
Product Name:Ezetimibe Related Impurity 37
Synonyms:Ezetimibe Related Impurity 7;Ezetimibe Anhydro (E)-Isomer;3’-Anhydro Ezetimibe;2-Azetidinone, 1-(4-fluorophenyl)-3-[(2E)-3-(4-fluorophenyl)-2-propen-1-yl]-4-(4-hydroxyphenyl)-, (3R,4S)-;-AnhydroEzetimibe;Ezetimibe alkene impurity;Ezetimibe Impurity 111;Ezetimibe Impuriry 37
CAS:204589-68-4
MF:C24H19F2NO2
MW:391.41
EINECS:
Product Categories:
Mol File:204589-68-4.mol
Ezetimibe Related Impurity 37 Structure
Ezetimibe Related Impurity 37 Chemical Properties
Melting point 177-179°C
Boiling point 625.7±55.0 °C(Predicted)
density 1.303±0.06 g/cm3(Predicted)
storage temp. Amber Vial, -20°C Freezer
solubility Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
pka9.72±0.30(Predicted)
form Solid
color Light Beige
Stability:Light sensitive
Safety Information
MSDS Information
Ezetimibe Related Impurity 37 Usage And Synthesis
Uses3’-Anhydro Ezetimibe is a metabolite of Ezetimibe (E975000), an antihyperlipoproteinemic which is a cholesterol absorption inhibitor.
Ezetimibe Related Impurity 37 Preparation Products And Raw materials
(R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one 3-O-Acetyl Ezetimibe (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopenyl]-4-phenyl-2-oxazolidinone Ezetimibe-13C6 EzetiMibe Dehydoxy IMpurity (3R,4S)-1-(4-chlorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (3R,4S)-1-(3-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Impurity 55 (2R,3R,6S)-N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxaMide (3S,4R)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one Ezetimibe Benzyl Impurity Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate EzetiMibe LactaM Cleaved Alcohol Ezetimibe (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One (4s)-3-((2r,5s)-5-(4-fluorophenyl)-2-((s)-((4-fluorophenyl)amino)(4-(phenylmethoxy)phenyl)methyl)-5-hydroxy-1-oxopentyl)-4-phenyl-2-oxazolidinone 3-[(2R,5S)-5-(4-Fluorophenyl)-2-[(S)-[(4-fluorophenyl(amino)]][4-[trimethylsilyl]-oxy]phenyl]methyl]-1-oxo-5-[(trimethylsily)-oxy]pentyl]-4-phenyl-(4S)-2-oxazolidinone EzetiMibe IMpurity 1
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