ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester

((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester

((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester Basic information
Product Name:((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester
Synonyms:((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester;(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-oxopropan-2-yl)carbamate;[(1R)-2-(Biphenyl-4-yl)-1-formylethyl]carbamic acid tert-butyl ester;((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl este;(R)-α-[[(1,1-dimethylethoxy)carbonyl]amino][1,1'-biphenyl]-4-propanal;LCZ-696-002-R;LCZ696(valsartan + sacubitril) impurity 23;Valsartan Impurity 68
CAS:149709-58-0
MF:C20H23NO3
MW:325.4
EINECS:
Product Categories:LCZ696
Mol File:149709-58-0.mol
((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester Structure
((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester Chemical Properties
Boiling point 475.1±45.0 °C(Predicted)
density 1.097±0.06 g/cm3(Predicted)
pka11.17±0.46(Predicted)
Safety Information
MSDS Information
((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester Usage And Synthesis
Usestert-?Butyl (R)?-?(1-?([1,?1''-Biphenyl]?-?4-?yl)?-?3-?oxopropan-?2-?yl)?carbamate is an impurity of LCZ696 (L270005), a novel dual-acting inhibitor of angiotensin II receptor and neprilysin, which can be used for blood pressure reduction.
((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester Preparation Products And Raw materials
Preparation Products(R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate
(R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoate (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid hydrochloride (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid Valsartan 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate AHU-377 (heMicalciuM salt) (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid LCZ696 InteMediate (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate LCZ696 interMediate
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