ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 4-Nitro-2-phenoxyphenol

4-Nitro-2-phenoxyphenol

4-Nitro-2-phenoxyphenol Basic information
Product Name:4-Nitro-2-phenoxyphenol
Synonyms:4-Nitro-2-phenoxyphenol;Phenol, 4-nitro-2-phenoxy-;4-Nitro-2-phenoxyphenol (Nimesulide Impurity)
CAS:70995-08-3
MF:C12H9NO4
MW:231.2
EINECS:
Product Categories:
Mol File:70995-08-3.mol
4-Nitro-2-phenoxyphenol Structure
4-Nitro-2-phenoxyphenol Chemical Properties
Melting point 63℃ (ligroine )
Boiling point 358.2±37.0 °C(Predicted)
density 1.357±0.06 g/cm3(Predicted)
storage temp. -20°C, Inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka5.76±0.16(Predicted)
color Pale Yellow to Light Yellow
Safety Information
MSDS Information
4-Nitro-2-phenoxyphenol Usage And Synthesis
Uses4-?Nitro-?2-?phenoxyphenol is a impurity of Nimesulide (N477500), antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production. Also used in the preparation of benzoxirenes and the synthesis of trioxonins.
4-Nitro-2-phenoxyphenol Preparation Products And Raw materials
Nimesulide N-(Methylsulfonyl)-4'-nitro-2'-phenoxyMethanesulfonanilide 4-HYDROXY NIMESULIDE (2-PHENOXY)METHYLSULFONYLANILINE 4',6'-Dinitro-2'-phenoxymethanesulfonanilide 2-Phenoxyaniline N-(Methylsulfonyl)-N-(2-phenoxyphenyl)MethanesulfonaMide NiMesulide EP IMpurity N-[4-nitro-2-(2,3,4,5,6-pentadeuteriophenoxy)phenyl]methanesulfonamide
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