1,2-Bis(piperazin-1-yl)benzene

1,2-Bis(piperazin-1-yl)benzene Basic information
Product Name:1,2-Bis(piperazin-1-yl)benzene
Synonyms:1,2-Bis(piperazin-1-yl)benzene;1,1'-(1,2-Phenylene)dipiperazine;Vortioxetine Impurity R: 1- (2-piperazine-1-phenyl) piperazine;Piperazine, 1,1'-(1,2-phenylene)bis-;Vortioxetine Impurity 20;1,2-di(piperazin-1-yl)benzene;VortioxetineImpurity20DiHCl;1,2-Di(piperazin-1-yl)benzene (Vortioxetine Impurity)
CAS:1446750-99-7
MF:C14H22N4
MW:246.35
EINECS:
Product Categories:
Mol File:1446750-99-7.mol
1,2-Bis(piperazin-1-yl)benzene Structure
1,2-Bis(piperazin-1-yl)benzene Chemical Properties
Boiling point 432.6±40.0 °C(Predicted)
density 1.089±0.06 g/cm3(Predicted)
pka9.22±0.10(Predicted)
Safety Information
MSDS Information
1,2-Bis(piperazin-1-yl)benzene Usage And Synthesis
Uses1,2-Di(piperazin-1-yl)benzene is an impurity of the antidepressant vortioxetine .
1,2-Bis(piperazin-1-yl)benzene Preparation Products And Raw materials
1-(2-BROMOPHENYL)PIPERAZINE 1-[2-[(2,4-diMethylphenyl)thio]phenyl]-4-[2-(1-piperazinyl)phenyl]- Piperazine Vortioxetine Impurity 5 Vortioxetine iMpurity 3,5-DIMETHYLTHIOPHENOL di(2,4-xylyl) disulphide 1-[2-[(5-chloro-2,4-diMethylphenyl)thio]phenyl]- Piperazine (2,4-diMethylphenyl)(2-nitrophenyl)sulfane Vortioxetine Impurity 4 Vortioxetine Impurity 25 1-[2-[(2,4-diMethylphenyl)sulfinyl]phenyl]- Piperazine Vortioxetine Impurity 1 1-[2-[(3,4-diMethylphenyl)thio]phenyl]- Piperazine 2,4-DIMETHYLDIPHENYLSULFIDE Vortioxetine impurity S 2,5-DIMETHYLTHIOPHENOL 3,4-DIMETHYLTHIOPHENOL Vortioxetine Impurity 37 HCl

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