Acetone thiosemicarbazone

Acetone thiosemicarbazone Basic information
Product Name:Acetone thiosemicarbazone
Synonyms:Thiosemicarbazone acetone;thiosemicarbazoneacetone;thiosemicarbazoneacetone[qr];ACETONE THIOSEMICARBAZIDE;ACETONE THIOSEMICARBAZONE;2-(1-METHYLETHYLIDENE)HYDRAZINECARBOTHIOAMIDE;IFLAB-BB F0777-0579;1-(1-Methylethylidene)thiosemicarbazide
CAS:1752-30-3
MF:C4H9N3S
MW:131.2
EINECS:217-137-9
Product Categories:
Mol File:1752-30-3.mol
Acetone thiosemicarbazone Structure
Acetone thiosemicarbazone Chemical Properties
Melting point 174-175°C
Boiling point 213.8±23.0 °C(Predicted)
density 1.142 (estimate)
refractive index 1.5800 (estimate)
solubility soluble in Acetone
pka12.20±0.70(Predicted)
form powder to crystal
color White to Light yellow
InChIKeyFQUDPIIGGVBZEQ-UHFFFAOYSA-N
CAS DataBase Reference1752-30-3(CAS DataBase Reference)
NIST Chemistry Reference2-(1-Methylethylidene)hydrazinecarbothioamide(1752-30-3)
EPA Substance Registry SystemAcetone thiosemicarbazide (1752-30-3)
Safety Information
Risk Statements 21-25-26
Safety Statements 22-28-36/37/39
RIDADR 2811
RTECS AL7350000
HS Code 2930.90.9250
HazardClass 6.1
PackingGroup I
Hazardous Substances Data1752-30-3(Hazardous Substances Data)
Toxicitymouse,LD50,intraperitoneal,23mg/kg (23mg/kg),BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Journal of Pharmacology and Experimental Therapeutics. Vol. 122, Pg. 110, 1958.
MSDS Information
Acetone thiosemicarbazone Usage And Synthesis
Chemical PropertiesAcetone thiosemicarbazide is a white to yellow crystalline solid
General DescriptionSolid.
Reactivity ProfileAcetone thiosemicarbazone may form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. Explosive combination may occur with strong oxidizing agents, metal salts, peroxides, and sulfides. Emits toxic fumes of oxides of sulfur and nitrogen when heated to decomposition [Sax, 9th ed., 1996, p. 3165].
Health HazardHigh oral toxicity.
Fire HazardWhen heated to decomposition, Acetone thiosemicarbazone emits very toxic fumes of nitrogen oxides and sulfur oxides. Avoid decomposing heat.
Potential ExposureAcetone thiosemicarbazone is used as an intermediate in the manufacture of pharmaceuticals and pesticides. May be used as an agricultural chemical.
ShippingUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides
Waste DisposalIt is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator.
Acetone thiosemicarbazone Preparation Products And Raw materials
Preparation Productsmodified filling agent SBR-->preservative use for industry 1^<#^>-->acetone hydrazone-->subathizone
N-Aminothiourea N1-(4-METHOXYPHENYL)-2-[2-BROMO-1-(4-METHYLPHENYL)ETHYLIDENE]-1-(2-HYDROXYETHYL)HYDRAZINE-1-CARBOTHIOAMIDE N1-(4-METHYLPHENYL)-2-(4-CHLORO-1-PHENYLBUTYLIDENE)HYDRAZINE-1-CARBOTHIOAMIDE N-METHYLISATIN-3-THIOSEMICARBAZONE N1-(2-CHLOROPHENYL)-2-(2-BROMO-1-PHENYLETHYLIDENE)-1-METHYLHYDRAZINE-1-CARBOTHIOAMIDE 4-AMINO-6-METHYL-3-THIOXO-2,3,4,5-TETRAHYDRO-1,2,4-TRIAZIN-5-ONE ISATIN, 3-(4-PHENYLTHIOSEMICARBAZIDE) Phenylacetone N1-(4-CHLOROBENZYL)-2-(2-BROMO-1-PHENYLETHYLIDENE)-1-(2-HYDROXYETHYL)HYDRAZINE-1-CARBOTHIOAMIDE N1-(2,4-DIMETHYLPHENYL)-2-[4-CHLORO-1-(4-FLUOROPHENYL)BUTYLIDENE]HYDRAZINE-1-CARBOTHIOAMIDE Calcium pyruvate Pyruvic acid Thiocarbohydrazide N1-(2-CHLOROPHENYL)-2-[1-(BROMOMETHYL)-2,2-DIMETHYLPROPYLIDENE]-1-METHYLHYDRAZINE-1-CARBOTHIOAMIDE N1-[4-(TRIFLUOROMETHOXY)PHENYL]-2-(2-BROMO-1-PHENYLETHYLIDENE)-1-(2-HYDROXYETHYL)HYDRAZINE-1-CARBOTHIOAMIDE Acetone thiosemicarbazone gloxazone Diacetone Alcohol

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