ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 3-HYDROXY DESLORATADINE HCL

3-HYDROXY DESLORATADINE HCL

3-HYDROXY DESLORATADINE HCL Basic information
Product Name:3-HYDROXY DESLORATADINE HCL
Synonyms:3-HYDROXY DESLORATADINE HCL;8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol;Sch 45581;8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-β]pyridin-3-ol;5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-;Loratadine Desethoxycarbonyl 3-Hydroxy IMpurity;3-OH-desloratadine-D4 Hbr;Desloratadine 3-Hydroxy Impurity
CAS:119410-08-1
MF:C19H19ClN2O
MW:326.82
EINECS:
Product Categories:Heterocycles;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:119410-08-1.mol
3-HYDROXY DESLORATADINE HCL Structure
3-HYDROXY DESLORATADINE HCL Chemical Properties
Melting point 169-171°C
Boiling point 575.2±50.0 °C(Predicted)
density 1.292
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMF: 10 mg/ml; DMF:PBS(pH 7.2)(1:6): 0.14 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
pka9.27±0.20(Predicted)
Safety Information
MSDS Information
3-HYDROXY DESLORATADINE HCL Usage And Synthesis
Chemical PropertiesLight Brown Solid
Uses3-Hydroxy Desloratadine is an active metabolite of Loratadine.
3-HYDROXY DESLORATADINE HCL Preparation Products And Raw materials
Loratadine 2-Chloro IMpurity N-ForMyl Desloratadine Chloropyramine hydrochloride Loratadine 8-Dechloro-7-chloro Loratadine 8-Dechloro-10-chloro Loratadine Desloratadine N-Hydroxypiperidine 3-METHOXY-N-METHYLDESLORATADINE Desloratadine 3-Hydroxy Desloratadine b-D-Glucuronide 3-HYDROXY DESLORATADINE HCL 3-METHOXY DESLORATADINE 3-Methoxy Loratadine
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