ChemicalBook Product Catalog Chemical Reagents Organic reagents Amide 2-CHLORO-N-METHOXY-N-METHYLACETAMIDE

2-CHLORO-N-METHOXY-N-METHYLACETAMIDE

2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Basic information
Product Name:2-CHLORO-N-METHOXY-N-METHYLACETAMIDE
Synonyms:2-CHLORO-N-METHOXY-N-METHYLACETAMIDE;2-CHLORO-N-METHOXY-N-METHYLACETAMIDE, 98 %;Methyl 2-Chloro-N-methylacetohydroxamate;N-(Chloroacetyl)-N-methoxymethylamine;AcetaMide, 2-chloro-N-Methoxy-N-Methyl-;N-Methyl-N-methoxy-2-chloroacetamide;2-Chloro-N-methoxy-N-methylacetamide,97%;N-(Chloroacetyl)-N-methoxymethylamine, N-(2-Chloroethanoyl)-N-methoxymethylamine
CAS:67442-07-3
MF:C4H8ClNO2
MW:137.56
EINECS:
Product Categories:Halides;Amides;Carbonyl Compounds;Organic Building Blocks
Mol File:67442-07-3.mol
2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Structure
2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Chemical Properties
Melting point 39-41 °C(lit.)
Boiling point 94-95 °C
density 1.178±0.06 g/cm3 (20 ºC 760 Torr)
Fp 220 °F
storage temp. 2-8°C
form Crystals
color White to light yellow
Water Solubility Insoluble in water.
BRN 1924015
InChIKeySCOJKGRNQDKFRP-UHFFFAOYSA-N
CAS DataBase Reference67442-07-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22
Safety Statements 23-26-27-28-37/39
WGK Germany 3
HS Code 29241900
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Usage And Synthesis
Chemical Propertieswhite to light yellow crystals
Uses2-Chloro-N-methoxy-N-methylacetamide is used in the preparation of 2-heptyl-3-hydroxy-4(1H)-quinolone (Pseudomonas quinolone signal or PQS) and structurally related 2-alkyl-4-quinolones having biological activity, 2-(benzo[d]thiazol-2-ylsulfonyl)-N-methoxy-N-methylacetamide and α-chloro-ketone, starting reagent for the one-pot synthesis of 2-heptyl-3-hydroxyl-4(1H)-quinolone (PQS), signaling molecule in the quorum sensing of Pseudomonas aeruginosa.
General Description2-Chloro-N-methoxy-N-methylacetamide is a Weinreb amide.
2-CHLORO-N-METHOXY-N-METHYLACETAMIDE Preparation Products And Raw materials
Preparation ProductsN-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE-->Ethanone, 1-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2-chloro--->2-iodo-N-methoxy-N-methylacetamide-->2-chloro-1-(6-(2,5-dimethyl-1H-pyrrol-1-yl)pyridin-3-yl)ethanone
O-(4-NITROBENZYL)HYDROXYLAMINE HYDROCHLORIDE N-Methylacetamide 4-CHLORO-N-METHOXY-N-METHYLACETAMIDE 1-[3A,11C-DIHYDRO-3H-BENZO[5,6]CHROMENO[4,3-C]ISOXAZOL-1(4H)-YL]-2-CHLORO-1-ETHANONE N-Methoxy-N-methylacetamide 2-(CHLOROACETYL)-5-METHYLISOXAZOL-3(2H)-ONE CS 722 2-CHLORO-N-METHOXY-N-METHYLACETAMIDE
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