ChemicalBook Product Catalog Biochemical Engineering Inhibitors PI3K / Akt / mTOR PI3K inhibitor CZC24832

CZC24832

CZC24832 Basic information
Product Name:CZC24832
Synonyms:CZC24832;5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide;3-Pyridinesulfonamide, 5-(2-amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-;5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide CZC 24832;CZC 24832 5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide;5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide;CZC 24832;CZC-24832;CS-957
CAS:1159824-67-5
MF:C15H17FN6O2S
MW:364.4
EINECS:200-258-5
Product Categories:Akt;mTOR;PI3K/Akt/mTOR;Inhibitors;PI3K
Mol File:1159824-67-5.mol
CZC24832 Structure
CZC24832 Chemical Properties
density 1.51
storage temp. Store at -20°C
solubility insoluble in H2O; insoluble in EtOH; ≥6.07 mg/mL in DMSO with gentle warming
form solid
pka10.29±0.50(Predicted)
Safety Information
MSDS Information
CZC24832 Usage And Synthesis
UsesCZC24832 is a selective phosphoinositide 3-kinase γ (PI3Kγ) inhibitor. CZC24832 regulates interleukin-17-producing T helper cell (TH17) differentiation by PI3Kγ thus making CZC24832 a potential treatment for inflammatory and autoimmune diseases.
CZC24832 Preparation Products And Raw materials
4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE, 7-METHYL-2-(4-MORPHOLINYL)-9-[1-(PHENYLAMINO)ETHYL]- IC-87114 Trametinib CAL-101 Alpelisib (BYL719) WZ4003
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