ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Basic information
Product Name:(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Synonyms:(2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one;(2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib);(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one;(E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one;Imatinib EP Impurity A (Nilotinib Impurity 16);Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one;(E)-3-(dimethylamino)
CAS:123367-26-0
MF:C10H12N2O
MW:176.22
EINECS:
Product Categories:
Mol File:123367-26-0.mol
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Structure
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties
Melting point 113℃
Boiling point 281℃
density 1.070
Fp 124℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka4.74±0.70(Predicted)
form Solid
color Dark Brown to Very Dark Brown
Safety Information
MSDS Information
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Usage And Synthesis
Uses(2E)?-?3-?(Dimethylamino)?-?1-?(3-?pyridyl)?prop-?2-?en-?1-?one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents.
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials
4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide N-DESMETHYL IMATINIB N-(2-Methyl-4-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)- (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one (S)-Ibrutinib Imatinib Impurity 7 Ibrutinib Dimer Impurity Ibrutinib Impurity 5 Imatinib Impurity 4 (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone Ibrutinib Impurity 28 Imatinib Impurity 38 2-Propen-1-one, 1-[(3R)-3-[4-amino-7-oxido-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- Ibrutinib iMpurity N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE Ibrutinib Impurity D Ilutinib Methylxanthate Impurity C
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