1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol

1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol Basic information
Product Name:1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol
Synonyms:O-Desmethyl-N,N-didesmethylvenlafaxine;Tridesmethylvenlafaxine;D,L-N,N-DidesMethyl-O-desMethyl Venlafaxine;4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]phenol;Desvenlafaxine N,N-Didesmethyl Imp;Desvenlafaxine Impurity 6;O,N,N tri desmethyl Venlafaxine;N,N-Didesmethyldesvenlafaxine
CAS:149289-29-2
MF:C14H21NO2
MW:235.32204
EINECS:1533716-785-6
Product Categories:
Mol File:149289-29-2.mol
1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol Structure
1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol Chemical Properties
Melting point >182°C (dec.)
Boiling point 405.0±20.0 °C(Predicted)
density 1.179
storage temp. Hygroscopic, Refrigerator, under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
pka9.72±0.26(Predicted)
form Solid
color White to Beige
Stability:Hygroscopic
Safety Information
MSDS Information
1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol Usage And Synthesis
UsesD,L-N,N-Didesmethyl-O-desmethyl Venlafaxine is a metabolite of Venlafaxine (V120000), a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant.
1-[2-amino-1-(4-hydroxyphenyl)ethyl]cyclohexanol Preparation Products And Raw materials
Raw materialssodium dodecane-1-thiolate-->1-Dodecanethiol-->Dodecyl methyl sulfide-->O-Desmethylvenlafaxine
Preparation ProductsVenlafaxine N-Dimer
DESVENLAFAXINE SUCCINATE R-(-)-O-DESMETHYLVENLAFAXINE O-Desmethyl Gefitinib-d6 O-Desmethyl Pantoprazole O-SulfateDiscontinued Desvenlafaxine (O-DesMethyl Venlafaxine) FuMarate O-DESMETHYL-N,N-DIDESMETHYL VENLAFAXINE HCL D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine Venlafaxine N-Dimer 2-(2-Aminoethylamino)ethanol O-Desmethyl Venlafaxine Glucuronide Lithium Salt O-DESMETHYL PANTOPRAZOLE O-SULFATE 7-DeMethyl Ivabradine rac Dehydro-O-desMethyl Venlafaxine R-VENLAFAXINE D,L N,O-Didesmethylvenlafaxine S-(+)-O-DESMETHYL VENLAFAXINE O-DesMethyl Venlafaxine Cyclic IMpurity O-DesMethyl Ivabradine

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