2’’-Desethyl-2’’-vinyl Simvastatin

2’’-Desethyl-2’’-vinyl Simvastatin Basic information
Product Name:2’’-Desethyl-2’’-vinyl Simvastatin
Synonyms:2’’-Desethyl-2’’-vinyl Simvastatin;(1S,3R,7S,8S)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbut-3-enoateMethylene simvastatin;Simvastatin Impurity 7(Simvastatin EP Impurity G);3-Butenoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester;Simvastatin Impurity 7(EP-G);(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbut-3-enoate;Simvastatin EP Impurity G/ Simvastatin Related Compound G (Simvastatin-3-en/ Methylene simvastatin);Methylene Simvastatin ((1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethy (1428229)
CAS:1449248-72-9
MF:C25H36O5
MW:416.55
EINECS:
Product Categories:Chiral Reagents;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:1449248-72-9.mol
2’’-Desethyl-2’’-vinyl Simvastatin Structure
2’’-Desethyl-2’’-vinyl Simvastatin Chemical Properties
Melting point 126 - 130°C
Boiling point 569.9±50.0 °C(Predicted)
density 1.12±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Acetone (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
pka13.49±0.40(Predicted)
form Solid
color White to Off-White
Safety Information
HS Code 2932206000
MSDS Information
2’’-Desethyl-2’’-vinyl Simvastatin Usage And Synthesis
Uses2’’-Desethyl-2’’-vinyl Simvastatin (Simvastatin EP Impurity G) is a Simvastatin (S485000) impurity.
2’’-Desethyl-2’’-vinyl Simvastatin Preparation Products And Raw materials
Simvastatin Acyl-b-D-glucuronide Simvastatin Hydroxy Acid Methyl Ester SiMvastatinAcetate Ester 3(S)-Hydroperoxy Simvastatin Simvastatin Dimer SiMvastatin EP IMpurity G 2′-Ethyl Simvastatin SiMvastatin 4'-Methyl Ether SiMvastatin EP IMpurity G Epi Lovastatin SiMvastatin IMpurity H AnhydrosiMvastatin SiMvastatin Methyl Ester 6'-EXOMETHYLENE SIMVASTATIN SiMvastatin Hydroxy Acid Ethyl Ester SIMVASTATIN, SODIUM SALT 3”-HYDROXY SIMVASTATIN Dehydro Simvastatin

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