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| | FUCHSIN BASIC Basic information |
| | FUCHSIN BASIC Chemical Properties |
| Melting point | 250 °C | | Boiling point | 300℃[at 101 325 Pa] | | density | 0.999 g/mL at 20 °C | | vapor pressure | 0Pa at 25℃ | | refractive index | n20/D 1.334 | | Fp | 48 °F | | storage temp. | 2-8°C | | solubility | H2O: soluble1mg/mL | | form | liquid | | Colour Index | 42510 | | color | Green to dark green | | PH | 5-6 (1g/l, H2O, 25°C) | | Water Solubility | 4 G/L (25 ºC) | | λmax | 543 nm | | Merck | 14,5652 | | BRN | 4166684 | | Biological Applications | Detecting cancer; treating Jock itch,oral fungal infection,piles; periodontal disease | | LogP | 1.632 at 25℃ | | IARC | 2B (Vol. Sup 7, 57, 99, 100F) 2012 | | EPA Substance Registry System | C.I. Basic Violet 14 (632-99-5) |
| | FUCHSIN BASIC Usage And Synthesis |
| Chemical Properties | Green crystal powder | | Uses | Biological stain for distinguishing coli and aerogene bacteriaBasic Fuchsin is useful for Ziehl-Neelson staining to detect acid-fast bacilli. It is also used to stain tubercle bacillus and bacterial flagella. It plays an important role for tissue sections to visualize elastic fibers, cardiac and skeletal muscle tissue. It also acts as bacterial and histological stains. Further, it is used to stain cellular elements, certain tissues, bacteria and also acts as a local anti-infective. | | Uses | As a dye or in manufacture of other dyes. | | Definition | ChEBI: A hydrochloride that is the monohydrochloride of 4-[(4-aminophenyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-2-methylaniline. One of the major constituents of Basic fuchsin, together with pararosanilin, magenta II and new fuchsin. | | General Description | Dark green powder. A dye derived from triphenylmethane. | | Air & Water Reactions | Slightly soluble in water. | | Reactivity Profile | FUCHSIN BASIC neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Easily reduced to colorless leuco-bases . | | Fire Hazard | Flash point data for FUCHSIN BASIC are not available, but FUCHSIN BASIC is probably combustible. | | Flammability and Explosibility | Notclassified | | Clinical Use | Basic fuchsin is a mixture of the chlorides of rosaniline andp-rosaniline. It exists as a green crystalline powder with ametallic appearance. The compound is soluble in water andin alcohol but insoluble in ether. Basic fuchsin is a componentof carbol–fuchsin solution (Castellani’s paint), which isused topically in the treatment of fungal infections, notablyringworm and athlete’s foot. | | Purification Methods | Purify the dye by dissolving it in EtOH, filtering and adding H2O. Filter or centrifuge it and wash the precipitate with Et2O and dry it in air. It has also been recrystallised from water and dried in vacuo at 40o. The crystals have a metallic green lustre. It has UV max in EtOH at 543nm ( 93,000). Its solubility in H2O is 0.26%. A carmine red colour is obtained in EtOH. It is paraRosaniline with a methyl group. [Scalan J Am Chem Soc 57 887 1937.] | | Properties and Applications |
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TEST ITEMS
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SPECIFICATION
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APPEARANCE
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VIOLET
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LIGHTING
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4-5
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SOAPING
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4-5
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PERSPIRATING
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4-5
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FRICTION(DRY)
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4-5
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FRICTION(WET)
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4
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RESIDUE ON 80 MESH
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5.0% max
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WATER SOLUBLE
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1.0% max
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VOLATITE 105 °C
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1.0% max
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TINTING STRENGTH
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100-105 %
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WEIGHT METAL TOTAL
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50ppm max
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| | FUCHSIN BASIC Preparation Products And Raw materials |
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